[3P] Neurogenesis and Gliogenesis

[3P-002] Among the more than 50 clustered protocadherin (cPcdh), PcdhγC4 is the only isoform that is essential for mice survival and that confers diversity to cPcdh.

〇Ryuon Higuchi¹, Natsumi Hoshino¹, Masahiko Watanabe², Makoto Sambo³, Akira Hagi¹, Tomoki Osuka¹, Masumi Hirabayashi³, Takeshi Yagi¹ (1.KOKORO-Biology Group, Graduate School of Frontier Biosciences, Osaka University, Suita, Japan, 2.Department of Anatomy and Embryology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 3.Section of Mammalian Transgenesis, Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, Okazaki, Japan)

Keywords:clustered protocadherin, neural circuit formation, protein-protein interaction, CRISPR/Cas9