Loss of DNA polymerase β induces DNA double-strand breaks in neural progenitors of human iPSC-derived cerebral organoids

Sayaka Chiba, Kouki Masuta, Hiroto Tsunematsu, Aya Kurosawa, Noritaka Adachi, Nobuhiko Yamamoto, Takeshi Yagi, Noriyuki Sugo

[3P-004] Loss of DNA polymerase β induces DNA double-strand breaks in neural progenitors of human iPSC-derived cerebral organoids

〇Sayaka Chiba¹, Kouki Masuta¹, Hiroto Tsunematsu¹, Aya Kurosawa², Noritaka Adachi², Nobuhiko Yamamoto¹, Takeshi Yagi¹, Noriyuki Sugo¹ (1.Graduate School of Frontier Biosciences, Osaka University, 2.Graduate School of Nanobioscience, Yokohama City University)

Keywords:Cerebral organoids, human induced pluripotent stem cell, DNA repair, DNA double-strand breaks

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[3P] Neurogenesis and Gliogenesis

[3P-004] Loss of DNA polymerase β induces DNA double-strand breaks in neural progenitors of human iPSC-derived cerebral organoids

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