[S05] Recent advances in the studies of metabolic syndromes and applications to the development of new drugs

[S05-5] Inhibition of plasminogen activator inhibitor-1 activation suppresses high fat diet-induced weight gain via alleviation of hypothalamic leptin resistance

○Tetsuya Yamada¹, Shinichiro Hosaka², Kei Takahashi², Hideki Katagiri² (1. Dep. of Mol. Endocrinol. and Metab., Tokyo Medical and Dental Univ., 2. Dep. of Metab. and Diabetes, Tohoku Univ.)