[26S-pm] Chemical Biology-2

Sat. Mar 26, 2022 2:42 PM - 3:42 PM [Room S] Conference Room 431 (Bldg. 4: 3F)

Chair: Kentaro Takayama

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2:42 PM - 2:54 PM

[26S-pm07S] Development of one-step fluorescence probes for sirtuin deacylation activity and their application

○Yuya Nakajima¹, Mitsuyasu Kawaguchi¹, Naoya Ieda¹, Hidehiko Nakagawa¹ (1. Organic and Medicinal Chemistry Lab., Graduate School of Pharmaceutical Sciences, Nagoya City University)

2:54 PM - 3:06 PM

[26S-pm08S] Development of intramolecular O-to-N phosphoryl transfer reaction-based fluorescent probes to detect hydrolytic activities of enzymes that recognize peptide main chain structures

○Risako Sawayama¹, Toru Komatsu¹, Yasuteru Urano^1,2 (1. Grad. Sch. Pharm. Sci., Univ. Tokyo, 2. Grad. Sch. Med., Univ. Tokyo)

3:06 PM - 3:18 PM

[26S-pm09S] Fluorescence analysis of heme-exporting ability of ABCG2 and the fluctuation of heme during ferroptosis with a heme-selective fluorescent probe

○Kanta Kawai¹, Tasuku Hirayama¹, Masatoshi Inden¹, Takanori Murakami¹, Mieko Tsuji¹, Hideko Nagasawa¹ (1. Gifu Pharm. Univ.)

3:18 PM - 3:30 PM

[26S-pm10S] Development and Application of Activatable PAI Probe

○Takafumi Kasai¹, Takeshi Hirasawa², Miya Ishihara², Yasuteru Urano^1,3 (1. Grad. Sch. Pharm. Sci., Univ. Tokyo, 2. Grad. Sch. Med., National Defense Medical College , 3. Grad. Sch. Med., Univ. Tokyo)

3:30 PM - 3:42 PM

[26S-pm11] Application of single enzyme activity-based protein profiling to liquid biopsy

○Shingo Sakamoto¹, Toru Komatsu¹, Rikiya Watanabe², Kazufumi Honda³, Tadahaya Mizuno¹, Yu Kagami¹, Hideto Hiraide¹, Nozomi Iwakura¹, Misa Suzuki¹, Yasuteru Urano^1,4,5 (1. Grad. Sch. Pharm. Sci., The Univ. Tokyo, 2. RIKEN, 3. Grad. Sch. Med., Nip. Med. Sch., 4. Grad. Sch. Med., The Univ. Tokyo, 5. AMED CREST)

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