[26T-pm] Drug design-2/Natural medicines and biological products-1

Sat. Mar 26, 2022 2:42 PM - 3:54 PM [Room T] Conference Room 432 (Bldg. 4: 3F)

Chair: Naohisa Ogo

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2:42 PM - 2:54 PM

[26T-pm07S] Selective Covalent Targetting of SARS-CoV-2 Main Protease by Enantiopure Chlorofluoroacetamide

○Daiki Yamane¹, Naoya Shindo¹, Satsuki Onitsuka¹, Suyong Re², Kenji Mizuguchi², Eiji Kawanishi¹, Akio Ojida¹ (1. Grad. Sch. Pharm. Sci, Kyushu Univ., 2. NIBIOHN)

2:54 PM - 3:06 PM

[26T-pm08S] Development of cancer matastasis inhibitors targeting at EMT

○Tsugumasa Toma¹, Hiroshi Tateishi¹, Kensaku Kawakami², Yuta Nakashima², Masami Otsuka^1,3, Mikako Fujita¹ (1. Grad. Sch. Pharm. Sci., kumamoto Univ, 2. Faculty of Advanced Science and Technology, kumamoto Univ, 3. SCIENCE FARM Ltd.)

3:06 PM - 3:18 PM

[26T-pm09S] Development of Novel Androgen Receptor Antagonists Based on Disubstituted Ferrocene

○Kotaro Ochiai¹, Hiroyuki Kagechika¹, Shinya Fujii¹ (1. Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University)

3:18 PM - 3:30 PM

[26T-pm10S] Synthesis of Lysophosphatidylserine Derivatives and Study of Anti-Fibrosis Effect

○Luying Chen¹, Yuko Otani¹, Taketomo Kido², Atsushi Miyajima², Tomohiko Ohwada¹ (1. Grad. Sch. Pharm. Sci., Univ. of Tokyo, 2. IQB, Univ. of Tokyo)

3:30 PM - 3:42 PM

[26T-pm11] Detoxification by curcumin derivative through dissociation of amyloid β fibrils and its verification in Drosophila Alzheimer's disease model

Rohmad Yudi Utomo¹, Atsushi Sugie², Satoshi Okada^1,3, Kazuki Miura^1,3, ○Hiroyuki Nakamura^1,3 (1. School of Life Science and Technology, Tokyo Institute of Technology, 2. Brain Research Institute, Niigata University, 3. Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology)

3:42 PM - 3:54 PM

[26T-pm12S] Exploratory study of novel metallo-β-lactamase inhibitors using in situ click chemistry

○Kiki Nakazato¹, Akari Ikeda^1,2, Akihiro Tomiyama¹, Yoshiki Ikegaya¹, Masako Honshou², Yukihiro Asami^1,2, Tomoyasu Hirose^1,2, Toshiaki Sunazuka^1,2 (1. Grad. Sch. Infection Control Sci., Kitasato Univ., 2. Ōmura Inst. Kitasato Univ.)

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