Symposium

[S20] Evaluation of health impact and risk analysis of chemical substances

Sun. Mar 27, 2022 9:30 AM - 11:30 AM [Room B] Conference Room 131+132 (Bldg. 1: 3F)

Organizer: Kazuma Higashisaka (Grad. Sch. Pharm. Sci., Osaka Univ.), Takuya Yamashita (Sch. Pharm. Sci., Wakayama Med. Univ.)

Chemical substances such as medicines, food additives, or cosmetics have become an integral part of our lives. As growing the recent interest in health, these are more strongly required to be safe. Thus, research to pursue their safety has become an important research and education issue in pharmaceutical sciences. For developing chemical substances that ensure human health, it is essential not only to understand the risks (integration of exposure and hazard) by analyzing their exposure level and health effects (hazard) of chemical substances, but to manage and control them. Moreover, based on the information, establishing a quality assurance and toxicity prediction evaluation system is also an issue to be tackled. Therefore, this symposium gives lectures about research on indispensable elements when considering the effects of chemical substances on human health; (1) understanding and controlling the pharmacokinetics, (2) elucidation of toxicity and its mechanism considering the difference in species, and (3) analytical chemistry for quality control. Together, we would like to discuss prospects for human health impact assessment and risk analysis.

+Add all to schedule

オーガナイザー挨拶：山下琢矢（和歌山県医大薬） (9:30 AM - 9:33 AM)

9:33 AM - 9:52 AM

[S20-1] Mechanistic analysis of drug-induced gastrointestinal toxicity: focusing on the impact of serotonin-associated gut microbiota dynamics

○Yoshiyuki Shirasaka¹ (1. Faculty of Pharmacy, Kanazawa University)

9:52 AM - 10:11 AM

[S20-2] Development of kidney-targeted drug delivery system using serine-modification

○Hidemasa Katsumi¹, Masaki Morishita¹, Akira Yamamoto¹ (1. Kyoto Pharmaceutical University)

10:11 AM - 10:30 AM

[S20-3] Understanding of multiple effects of low molecular weight compounds with factor analysis

○Tadahaya Mizuno¹, Shumpei Nemoto¹, Katsuhisa Morita¹, Hiroyuki Kusuhara¹ (1. Graduate School of Pharmaceutical Sciences, The University of Tokyo)

10:30 AM - 10:49 AM

[S20-4] Development of single reference HPLC method which has traceability based on relative molar sensitivity for application of quality evaluation

○Miki Takahashi¹ (1. Ritsumeikan University College of Pharmaceutical Sciences)

10:49 AM - 11:08 AM

[S20-5] Identification of the underlying principle of species difference in the chemical liver carcinogenesis

○Ryota Shizu¹, Kouichi Yoshinari¹ (1. Sch Pharm Sci, Univ Shizuoka)

11:08 AM - 11:27 AM

[S20-6] The effects of nanoparticles on nerve cell differentiation and its mechanisms for human health risk analysis

○Kazuma Higashisaka^1,2 (1. Grad. Sch. Pharm. Sci., Osaka Univ., 2. Inst. Adv. Co-Creation Stud., Osaka Univ.)

まとめ：東阪和馬（阪大院薬） (11:27 AM - 11:30 AM)

Session information