[27T-am] Alkaloids and nitrogen-containing natural products-2

Sun. Mar 27, 2022 10:30 AM - 11:30 AM [Room T] Conference Room 432 (Bldg. 4: 3F)

Chair: Haruhisa Kikuchi

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10:30 AM - 10:42 AM

[27T-am06S] Total synthesis and bioactivity of heat shock metabolites (HSM), maniwamycins produced by thermotolerant Streptomyces sp. JA74

○Kayo Funayama¹, Shun Saito¹, Wataru Kato¹, Kazutoshi Shindo², Meiko Kawamoto¹, Teruhiko Matsubara¹, Toshinori Sato¹, Satoko Otsuguro³, Katsumi Maenaka³, Masaya Imoto⁴, Midori A. Arai¹ (1. Fac. Sci. Tech., Keio Univ., 2. Fac. Human Sci. Design, Japan Women’s Univ., 3. Fac. Pharm. Sci., Hokkaido Univ., 4. Fac. Med., Juntendo Univ.)

10:42 AM - 10:54 AM

[27T-am07S] Amakusamine, a new indole alkaloid isolated from the marine sponge Psammocinia sp. collected in Amakusa, that inhibits osteoclastogenesis.

○Yuka Maeyama¹, Yuta Nakashima², Hikaru Kato¹, Yuki Hitora¹, Kazuhiko Maki¹, Natsumi Inada¹, Shunya Murakami¹, Hayato Ishikawa³, Sachiko Tsukamoto¹ (1. Grad. Sch. Pharm. Sci., Kumamoto Univ., 2. Grad. Sch. Sci. Tech., Kumamoto Univ., 3. Grad. Sch. Pharm. Sci., Chiba Univ.)

10:54 AM - 11:06 AM

[27T-am08S] Isolation, structure elucidation and asymmetric total synthesis of secorubenine, from Adina rubescens

○Jukiya Sakamoto¹, Nanako Nakashima^1,2, Mariko Kitajima¹, Lia D. Juliawaty³, Hayato Ishikawa¹ (1. Grad. Sch. Pharm. Sci., Chiba Univ., 2. Grad. Sch. Sci., Kumamoto Univ., 3. Org. Chem. Div., Inst. Technol. Bandung)

11:06 AM - 11:18 AM

[27T-am09] Micromonosporamide A with glutamine-dependent cytotoxicity: Isolation, stereochemical determination, and synthesis

○Toshifumi Takeuchi¹, Hideyuki Muramatsu¹, Kazuki Hatano¹, Yumiko Kubota¹, Ryuichi Sawa¹, Masayuki Igarashi¹ (1. Inst. Microbial Chem.)

11:18 AM - 11:30 AM

[27T-am10S] Asymmetric synthesis and biological evaluation of evodiamine analogs as TRPV1 agonists.

○Takahiro Furuta¹, Akari Ueno¹, Tomohisa Kanai¹, Yusuke Kawabata¹, Takako Utsuki¹, Tatsuya Shirahata¹, Shunsuke Nakamori¹, Naruki Konishi¹, Toshiko Kagawa (Tanaka)², Hideto Jinno³, Yoshinori Kobayashi¹ (1. Sch. of Pharm. Kitasato Univ. , 2. Yokohama Univ. of Pharm., 3. Faculty of Pharm., Meijo Univ.)

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