The 142nd Annual Meeting of the Pharmaceutical Society of Japan (Nagoya)

Presentation information

Oral Presentation

(A) Pharmaceutical Chemistry

[26J-pm] Other synthetic studies (Amino acids, peptides-1/Nucleic acids)

Sat. Mar 26, 2022 3:54 PM - 5:06 PM [Room J] Conference Room 223 (Bldg. 2: 2F)

Chair: Yosuke Taniguchi

4:30 PM - 4:42 PM

[26J-pm16S] Synthesis of gapmer oligonucleotides modified with prodrug type phosphotriester linkage and evaluation of their gene silencing effects

○Norihito Sugimoto1, Junsuke Hayashi1, Ryohei Funaki1, Emi Hozumi1, Fumito Wada2, Mariko Harada-Shiba2, Shun-ichi Wada1, Hidehito Urata1 (1. Faculty of Pharmacy, Osaka Medical and Pharmaceutical University, 2. National Cerebral and Cardiovascular Center Reseach Institute)

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