The 142nd Annual Meeting of the Pharmaceutical Society of Japan (Nagoya)

Presentation information

Poster Presentation

(C) Pharmaceutical Biology

[26PO5-am2] Digestive system-2/Chemotherapeutic agents/Others

Sat. Mar 26, 2022 10:50 AM - 12:30 PM [Room PO5] Bldgs. 2&3, 3F Passage (Bldgs. 2&3: 3F)

10:50 AM - 12:30 PM

[26PO5-am2-03] Methotrexate mediates the upregulation of intestinal stem cells partly through nitric oxide-dependent regulation of Lgr5 and sFRP-1 in methotrexate-induced rat ileal mucositis

○Maiko Machida1, Keita Minai1, Ayane Kumagai1, Koushirou Hayashi1, Yuto Masui1, Kaori Yama1, Saki Shiga2, Takuji Machida2, Masahiko Hirahuji2, Kenji Iizuka2 (1. Division of Pharmacotherapy, Faculty of Pharmaceutical Sciences, Hokkaido University of Science, 2. Department of Pharmacological Sciences, School of Pharmaceutical Sciences, Health Sciences University of Hokkaido)

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