Rational design of non-peptidic PDZ domain inhibitors of human Dvl1 based on the crystal structure of the target-inhibitor complex

Shotaro Yasukochi

1:42 PM - 1:54 PM

[27C-pm02] Rational design of non-peptidic PDZ domain inhibitors of human Dvl1 based on the crystal structure of the target-inhibitor complex

Shotaro Yasukochi¹, Nobutaka Numoto², Yuki Kamiya¹, Emi Hibino¹, Kiminori Hori¹, Natsuko Goda¹, Takeshi Tenno^1,3, Nobutoshi Ito², ○Hidekazu Hiroaki Hiroaki^1,3 (1. Grad. Sch. Pharm. Sci., Nagoya Univ., 2. Tokyo Med. Dent. Univ., 3. BeCerllBar, LLC.)

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Presentation information

[27C-pm] Structural biology-2/Intermolecular interaction-2

[27C-pm02] Rational design of non-peptidic PDZ domain inhibitors of human Dvl1 based on the crystal structure of the target-inhibitor complex

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