Prediction of Human Pharmacokinetics from Preclinical Information -Evaluation of predictive accuracy of Human Clearance classified by Metabolic Enzymes and Reconstruction of decision tree for the selection of prediction methods

○Masayoshi Miyamoto

10:50 AM - 12:30 PM

[27PO4-am2-06] Prediction of Human Pharmacokinetics from Preclinical Information -Evaluation of predictive accuracy of Human Clearance classified by Metabolic Enzymes and Reconstruction of decision tree for the selection of prediction methods

○Masayoshi Miyamoto¹, Katsumasa Otake¹, Takayuki Taguchi¹, Masanori Nakakariya¹, Takeshi Nakabayashi¹, Toshiyuki Takanohashi¹, Ryota Shigemi¹, Takafumi Iwatsubo¹, Mutsumi Suzuki¹ (1. JPMA)

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Presentation information

[27PO4-am2] ADME, PK/PD/Others

[27PO4-am2-06] Prediction of Human Pharmacokinetics from Preclinical Information -Evaluation of predictive accuracy of Human Clearance classified by Metabolic Enzymes and Reconstruction of decision tree for the selection of prediction methods

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