[3P-1064（3PT26-09）] CREG1 is a novel factor stimulating brown adipocyte differentiation in vivo

〇Michihiro Hashimoto¹, Tatsuya Kusudo², Tamaki Takeuchi¹, Hitoshi Yamashita¹ (1.Dept. of Biomed. Sci., Chubu Univ., 2.Fac. of Hum. Sci., Tezukayama Gakuin Univ.)

ConBio2017

[3P-1065（3PT26-10）] Prolyl isomerase Pin1 regulates the functions adipose tissues, and thereby being committed to obesity.

〇Yusuke Nakatsu¹, Takeshi Yamamotoya¹, Koji Ueda¹, Yuki Inoue¹, Masa-Ki Inoue¹, Yasuka Matsunaga¹, Tomoichiro Asano¹ (1.Dept. of Med. Sci., Grad. Sch. of Med., Hiroshima Univ.)

ConBio2017

[3P-1066（3PT26-12）] Metformin directly binds the alarmin HMGB1 and inhibits its proinflammatory activity

〇Natsumi Sakata¹, Takahiro Horiuchi¹, Yoshihiro Narumi¹, Tomohiro Kimura¹, Takashi Hayashi², Keisuke Nagano², Keyue Liu³, Masahiro Nishibori³, Sohei Tsukita⁴, Yamada Tetsuya⁴, Hideki Katagiri⁴, Ryutaro Shirakawa¹, Hisanori Horiuchi¹ (1.Dept. of Molecular and Cellular Biology, IDAC, Tohoku Univ., 2.Otsuka Pharmaceutical Co., Ltd., 3.Dept. of Pharmacology, Grad. Sch. of Med, Dent, and Pharmaceutical Sci., Okayama Univ., 4.Dept. of Metabolism and Diabetes, Grad. Sch. of Med, Tohoku. Univ.)

ConBio2017

[3P-1067（3PT26-13）] Intestinal FXR mediates a systemic regulation of functional Beta cells to ameliorate type1 and type2 diabetes

〇Eiji Yoshihara^1,3, Sungsoon Fang^1,3, Chun Shi Lin¹, Ting Fu¹, Zong Wei¹, Jae Myoung Suh¹, Ruth Yu¹, Ann T. Atkins¹, Michael Downes¹, Ronald M. Evans^1,2 (1.Gene Expression Laboratory, Salk Institute, 2.Howard Hughes Medical Institute, 3.Equally contribution)

ConBio2017

[3P-1068（3PT26-14）] Molecular mechanisms by which FGF19 improves NASH

〇Mei Tsuchida¹, Mayuka Yamada¹, Miki Takahashi¹, Yusuke Hirata¹, Masaaki Miyata², Kouichi Yoshinari^1,3, Takuya Noguchi¹, Atsushi Matsuzawa¹ (1.Lab. of Health Chem., Grad. Sch. of Pharmaceut. Sci., Tohoku Univ., 2.Dept. of Food Sci. Tech., National Fisheries Univ., 3.Grad. Sch. of Pharmaceut. Sci., Univ. of Shizuoka)

ConBio2017

[3P-1069（3PT26-15）] Regnase-1 maintains iron homeostasis via the destabilization of iron-regulatory transcripts

〇Masanori Yoshinaga¹, Takashi Mino¹, Osamu Takeuchi¹ (1.inFront, Kyoto Univ.)

ConBio2017

[3P-1070（4P1T06-01）] Adipocytes talk to macrophpges -insulin resistance promotes inflammation in adipose tissue-

〇Mitsugu Shimobayashi¹, Verena Albert¹, Bettina Woelnerhanssen², Irina Frei¹, Diana Weissenberger¹, Anne Christin Meyer-Gerspach², Nicolas Clement², Suzette Moes¹, Marco Colombi¹, Marta M. Swierczynska¹, Paul Jenoe¹, Jerome A. Meier¹, Christoph Beglinger², Peterli Ralph², Michael N. Hall¹ (1.UniBasel, BZ, 2.St. Claraspital)

ConBio2017

[3P-1071（4P1T06-02）] Nampt-mediated NAD synthesis regulates the differentiation of preadipocytes through the metabolic reprogramming

〇Keisuke Okabe^1,2, Isao Usui¹, Kazuyuki Tobe¹, Takashi Nakagawa² (1.1st. Dept. of Intern. Med., Grad. Sch. of Med., Univ. of Toyama , 2.Dept. of Metab. & Nutr., Grad. Sch. of Med., Univ. of Toyama)

ConBio2017

[3P-1072（4P1T06-03）] Effect of anti-obesity in transcription factor ChREBP deficient mice

〇Haruhiko Sakiyama¹, Minako Inoue¹, Tsutomu Nakagawa², Hironobu Eguchi¹, Daisaku Yoshihara¹, Noriko Fujiwara¹, Keiichiro Suzuki¹ (1.Dept. of Biochem., Hyogo. Col. of Med., 2.Div. of Pharmacokinet., Dept. of Biochem. Mol. Biol., Grad. Sch. of Med., Kobe Univ.)

ConBio2017

[3P-1073（4P1T06-04）] Heme deficiency casuses impaired glycogen metabolism through an elevation of cellular ATP levels

〇Shinichi Saitoh¹, Tsukasa Osaki², Hiroshi Nakano¹, Hidekazu Nohara¹, Satoshi Okano¹, Akitada Ichinose², Nobuyuki Shirasawa³, Akira Naitoh³, Masayuki Yamamoto⁴, Kelly P. Vincent⁵, Kiwamu Takahashi⁶, Tohru Tanaka⁶, Motowo Nakajima⁶, Osamu Nakajima¹ (1.Inst. for Prom. of Med. Sci., Fac. of Med., Yamagata Univ., 2.Dep. of Mol. Path., Fac. of Med., Yamagata Univ., 3.Dep. of Anat. I., Fac. of Med., Yamagata Univ., 4.Dep. of Med. Biochem., Tohoku Uni. Sch. of Med., 5.Trinity Biomed. Sci. Inst., Trinity Col. Dublin, 6.SBI Pharm. Co., Ltd.)

ConBio2017