[3P-1115] Identification of long non cording RNA ,CR18854 as a genetic interact Drosophila FIG4 a CMT-causeing gene

〇Yuuka Muraoka¹, Aya Nakamura¹, Ryo Tanaka¹, Yumiko Azuma², Yukie Kushimura², Luca Lo Piccolo¹, Koujirou Suda¹, Hideki Yoshida¹, Ikuko Mizuta³, Toshiki Mizuno², Takahiko Tokuda², Masamitsu Yamaguchi¹ (1.Dept. of Appl. Biol.,Kyoto Inst. of Technol , 2.Dept. of Neurol., Grad. Sch. of Med., Kyoto Pref. Univ. of Med., 3.Dept. of Mol. Pathobiol. of Brain Dis., Kyoto Pref. Univ. of Med.)

ConBio2017

[3P-1116] Characterization of brain pericyte-specific inflammation properties utilizing the new human brain vascular pericyte cell line

〇Kenta Umehara¹, Yuchen Sun¹, Atsunori Saraya³, Motohiko Oshima³, Atsushi Iwama³, Naohiko Anzai², Kan Chiba¹, Hidetaka Akita¹, Tomomi Furihata^1,2 (1.Lab. of Pharm. and Toxi., Grad. sch., of Parm., Chiba Univ., 2.Dept. of Pharm., Grad. sch., of Medi., Chiba Univ., 3.Dept. of Cell. and Medi., Grad. sch., of Medi., Chiba Univ.)

ConBio2017

[3P-1117] Improved method for isolating exosomes from brain and detection of amyloid β

〇Kento Fujisaki^1,2, Kyojiro Kawakami², Yasunori Fujita², Masayuki Yoshida¹, Masafumi Ito² (1.Dept. of Life Sci. Bioethics, Grad. Sch. of Med. Dent. Sci., Tokyo Med. Dent. Univ., 2.Mechanism of Aging, Tokyo Met. Inst. of Gerontol.)

ConBio2017

[3P-1118] Altered allele-specific gene expression by an ALS-causative TDP-43 mutation

〇Akihiro Sugai¹, Sachiko Hirokawa², Akihide Koyama³, Takuya Konno¹, Osamu Onodera¹ (1.Department of Neurology, Brain Research Institute, Niigata University, 2.Department of Molecular Neuroscience, Brain Research Institute, Niigata University, 3.Graduate School of Medical and Dental Sciences, Niigata University)

ConBio2017

[3P-1119] The analysis of Parkinsonʼs Disease (PD) candidate causative gene in a Drosophila melanogaster

〇Jo Shimizu¹, Takashi Kasai², Yumiko Azuma², Hideki Yoshida^3,4, Masamitsu Yamaguchi^3,4 (1.Dept. of Appl. Advan., Kyoto Inst. of Techno., 2.Dept. of Neurol., Grad. Sch. of Med., Kyoto Pref. Univ. of Med., 3.Dept. of Applied Biology, Kyoto Inst. of Technology, 4.Insect Biomed. Res.Center, Kyoto Inst. of Technology)

ConBio2017

[3P-1120] Mutations in the N-terminal self-interaction domain of ALS2 interfere the normal oligomeric state and endosomal localization of ALS2

〇Kai Sato¹, Asako Otomo^1,2, Mahoko Ueda², Jyunya Sugiyama¹, Suzuka Ono¹, Shun Mitsui¹, So Nakagawa^1,2, Shinji Hadano¹ (1.Dept. Mol. Life Sci., Med., Tokai Univ., 2.MNTC, Tokai Univ.)

ConBio2017

[3P-1121] An establishment and analysis of humanized GH model mice for dominantly inherited growth hormone deficiency.

〇Emika Kubo¹, Daisuke Ariyasu¹, Shinsuke Shibata², Kimi Araki¹ (1.Dept. of Dev. Genet., Res. Dev. and Analy., Univ. of Kumamoto, 2.Electron Microscope Lab., Univ. of Keio)

ConBio2017

[3P-1122] In vivo analysis using model mice of dominantly inherited growth hormone deficiency ~A decrease in the Ghrhr mRNA contributes to the pathogenesis of GH deficiency in the model mice~

〇Daisuke Ariyasu¹, Emika Kubo¹, Shinsuke Shibata², Kimi Araki¹ (1.Dev. Genet., Ins. of Res. Dev. Analy, Univ of Kumamoto, 2.Elect. Microsco. Lab, Univ of Keio)

ConBio2017

[3P-1123] The search for genes that modulate FUS-mediated phenotypes by Drosophila amyotrophic lateral sclerosis model

〇Yumiko Azuma¹, Takahiko Tokuda^1,2, Yukie Kushimura¹, Itaru Yamamoto^3,4, Ibuki Ueoka^3,4, Ikuko Mizuta¹, Toshiki Mizuno¹, Masanori Nakagawa^1,5, Morio Ueyama⁶, Yoshitaka Nagai⁶, Hideki Yoshida^3,4, Masamitsu Yamaguchi^3,4 (1.Dept. of Neurol., Grad. Sch. of Med., Kyoto Pref. Univ. of Med., 2.Dept. of Mol. Pathobiol. of Brain Dis., Kyoto Pref. Univ. of Med., 3.Dept. of Appl. Biol., Kyoto Inst. of Techno., 4.The Cent. for Adv. Insect Res. Promot., Kyoto Inst. of Techno. , 5.North Med. Cent., Grad. Sch. of Med., Kyoto Pref. Univ. of Med., 6.Dept. of Neurotherapeut., Grad. Sch. of Med., Univ. of Osaka. )

ConBio2017

[3P-1124（2PT26-01）] Nonsense-associated altered splicing leading to a human disorder: Identification of MAP3K1 mutations in two brothers with 46,XY disorders of sex development

〇Maki Igarashi¹, Kenichi Kinjo², Reiko Horikawa², Tsutomu Ogata³, Maki Fukami¹ (1.Dept. of Mol. Endocrinol., Inst. for NCCHD, 2.Dept. of Endocrinol. Metabo., Inst. for NCCHD, 3.Dept. of Pediatrics, Hamamatsu Univ. Sch. of Med.)

ConBio2017