[1P-291] Generation of pontocerebellar hypoplasia model zebrafish with CRISPR/Cas9 system

^○Hada Kazumasa, Tanaka Ryota, Urushibata Hakutarou, Inoue Masanori, Shiraishi Hiroshi, Hanada Toshikatsu (Oita University Faculty of Medicine)

The 91th Annual Meeting of JBS

[1P-292] Perturbation of gene regulation in an in vitro amelogenesis imperfecta model

^○Arinawati Dian Yosi¹, Miyoshi Keiko², Hagita Hiroko², Horiguchi Taigo², Noma Takafumi² (1.Graduate School of Oral Sciences, Tokushima University, 2.Department of Molecular Biology, Institute of Biomedical Sciences, Tokushima University Graduate School)

The 91th Annual Meeting of JBS

[1P-293] Identification and Characterization of novel Akt Inhibitors exerting specific anti-proliferative activity on malignant mesothelioma cells

^○Ota Akinobu¹, Yamaji Masayuki², Wahiduzzaman Md¹, Karnan Sivasundaram¹, Hyodo Toshinori¹, Konishi Hiroyuki¹, Tsuzuki Shinobu¹, Haniuda Masayuki², Hosokawa Yoshitaka¹ (1.Dept . Biochem., Aichi Med. Univ., Sch. Med., 2.Div. of Chest Surgery, Dept of Surgery, Aichi Med. Univ., Sch. Med.)

The 91th Annual Meeting of JBS

[1P-294] Effects of lithocholic acid on villin expression in HepG2 human hepatocarcinoma cells

^○Ozeki Munetaka, Tamaki Keiji (Department of Forensic Medicine, Graduate School of Medicine, Kyoto University)

The 91th Annual Meeting of JBS

[1P-295] Pain induction by mast cells in osteoarthritis model mouse

Habuchi Hiroko¹, Izumi Masashi², Dan Junpei², Ushida Takahiro¹, Ikeuchi Masahiko², ^○Habuchi Osami¹ (1.Multidisciplinary Pain Center, Aichi Medical University, 2.Department of Orthopaedic Surgery, Kochi Medical School, Kochi University)

The 91th Annual Meeting of JBS

[1P-296] Deactivation of TRPV2 prevents the progression to muscular dystrophy or dilated cardiomyopathy in the hamster model

^○Iwata Yuko, Hirayama Madoka, Ito Shin, Kitakaze Masafumi (Department of Clinical Rresearch and Development, National Cerebral and Cardiovasucular Center)

The 91th Annual Meeting of JBS

[1P-297] Importance of Src family kinases in the pathogenesis of inflammatory bowel disease

^○Sun Chunxiao^1,2, Murata Yoji¹, Imada Shinya¹, Kotani Takenori¹, Saito Yasuyuki¹, Yamada Hideto², Matozaki Takashi¹ (1.Div. Mol. & Cell. Signal., Kobe Univ. Grad. Sch. Med., 2.Dept. Ob. & Gyn., Kobe Univ. Grad. Sch. Med.)

The 91th Annual Meeting of JBS

[1P-298] Protective Effects of Brain Infarction by N-Acetylcysteine Derivatives

^○Uemura Takeshi¹, Watanabe Kenta², Ko Kenta², Higashi Kyohei², Kogure Noriyuki², Kitajima Mariko², Takayama Hiromitsu², Takao Koichi³, Sugita Yoshiaki³, Sakamoto Akihiko⁴, Terui Yusuke⁴, Toida Toshihiko², Kashiwagi Keiko⁴, Igarashi Kazuei^1,2 (1.Amine Pharma Res. Inst., 2.Grad. Sch. Pharm. Sci. Chiba Univ., 3.Lab. Bioorg. Chem., Dept. Pharm. Tech., Josai Univ., 4.Chiba Inst. Sci.)

The 91th Annual Meeting of JBS

[1P-299] Exposure to ultraviolet induces Otx2 expression in mouse lenses - effects of Otx2 overexpression in lens epithelial cells

Yoshitomi Yasuo¹, Osada Hiromi², Satake Haruka¹, ^○Takatsuji Hidehito¹, Ikeda Takayuki¹, Ishiyama Naofumi¹, Ishigaki Yasuhito³, Sasaki Hiroshi², Yonekura Hideto¹ (1.Dep of Biochem, Kanazawa Medical University, 2.Dept of Ophthal, Kanazawa Medical University, 3.Med Res Inst, Kanazawa Medical University)

The 91th Annual Meeting of JBS

[1P-300] Purification and evaluation of IgE binding affinity of cat allergen Fel d 4

^○Ubatani Miki¹, Sugiura Keisuke¹, Yamamoto Kenji¹, Fukutomi Yuma², Ishibashi Osamu¹, Inui Takashi¹ (1.Grad. Sch. of Life & Envi. Sci., Osaka Pref. Univ., 2.Clinical Res. Ctr. for Allergy & Rheumatol., Sagamihara Natl. Hosp.)

The 91th Annual Meeting of JBS