[1P-281] Inhibition of intestinal tumorigenicity in mice lacking TMEPAI gene involved in a negative feedback loop of TGF-β signaling

^○Shibasaki Teppei¹, Sano Keigo¹, Sawada Yutaro¹, Amano Syoei¹, Ishikawa Ryo¹, Ito Fumiko², Watanabe Yukihide³, Taketo Makoto M⁴, Kato Mitsuyasu³, Ito Susumu¹ (1.Laboratory of Biochemistry, Showa Pharmaceutical University, 2.Laboratory of Cardiovascular Medicine, Tokyo University of Pharmacy and Life Sciences, 3.Department of Experimental Pathology, Faculty of Medicine, University of Tsukuba, 4.Department of Pharmacology, Graduate School of Medicine, Kyoto University)

The 91th Annual Meeting of JBS

[1P-282] Establishment and characterization of novel murine pleomorphic rhabdomyosarcoma cell lines with KrasG12V expression and disruption of p53.

^○Saito Hiromitsu, Suzuki Noboru (Department of Animal Functional Genomics of Advanced Science Research Promotion Center,Organization for the Promotion of Regional Innovation)

The 91th Annual Meeting of JBS

[1P-283(1T14a-08)] Mechanisms underlying augmented lymphomagenesis by LUBAC; Possible accumulation of AID-mediated somatic mutations

^○Jo Tomoyasu^1,2, Nishikori Momoko², Takaori-Kondo Akifumi², Iwai Kazuhiro¹ (1.Department of Molecular and Cellular Physiology, Graduate School of Medicine, Kyoto University, 2.Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University)

The 91th Annual Meeting of JBS

[1P-284] Analysis of macrophage activating factor derived from murine T cell lymphoma EL4 cells

^○Kawakami Tomoya¹, Koike Atsushi², Fujimori Ko², Hayashi Tetsuya¹, Amano Fumio³ (1.Osaka University of Pharmaceutical Sciences, 2.Osaka University of Pharmaceutical Sciences, 3.Osaka University of Pharmaceutical Sciences)

The 91th Annual Meeting of JBS

[1P-285(1T14a-09)] Analysis of glycosylated epitopes on mucin-like membrane protein HEG1 in malignant mesothelioma

^○Matsuura Rieko¹, Imai Kohzoh^1,2, Tsuji Shoutaro¹ (1.Kanagawa Cancer Center Research Institute, Yokohama, Japan., 2.Institute of Medical Science, University of Tokyo, Tokyo, Japan.)

The 91th Annual Meeting of JBS

[1P-286(1T14a-10)] The Mg2+ transporter CNNM4 suppresses colon tumorigenesis

^○Yamazaki Daisuke, Hasegawa Ayaka, Funato Yosuke, Miki Hiroaki (Department of Cellular Regulation, Research Institute for Microbial Diseases, Osaka University)

The 91th Annual Meeting of JBS

[1P-287(1T14a-04)] Functional analysis of ASK1 in anti-tumor immunity

^○Fujimoto Makoto, Kamiyama Miki, Naguro Isao, Ichijo Hidenori (Laboratory of Cell Signaling, Graduate School of Pharmaceutical Sciences, The University of Tokyo)

The 91th Annual Meeting of JBS

[1P-288(1T14a-05)] Abnormal chromosomal regulation by malignancy driving protein PRL

^○Ryu Kajung, Yoshida Atsushi, Funato Yosuke, Yamazaki Daisuke, Miki Hiroaki (Department of Cellular Regualtion, Research institute for microbial Diseases, Osaka University)

The 91th Annual Meeting of JBS

[1P-289] A diagnostic method of Ehlers-Danlos syndromes with nano-LC/MS/MS

^○Yamada Kazuo^1,2, Watanabe Atsushi³, Kosho Tomoki⁴, Mizumoto Shuji⁵, Yamada Shuhei⁵, Takeshita Haruo¹, Matsumoto Ken-ichi² (1.Dept. of Leg. Med., Shimane Univ., 2.Dept. of Biosign. and Radioiso. Exp., Interdiscip. Cent. for Sci. Res., Org. for Res. Acad. Inform., 3.Div. of Clin. Genet., Nippon Med. Sch. Hosp., 4.Dept. of Med. Genet., Shinshu Univ., Sch. of Med., 5.Dept. of Pathobiochem. Fac. of Pharm. Meijo Univ.)

The 91th Annual Meeting of JBS

[1P-290] Analysis of X chromosome inactivation of 2 female patients harboring Xq27.1q28 deletion with different clinical features.

^○Katoh Kimiko¹, Aiba Kaori², Fukushi Daisuke¹, Suzuki Yasuyo¹, Yamada Kenichiro¹, Wakamatsu Nobuaki^3,4 (1.Department of Genetics, Institute for Developmental Research, Aichi Human Service Center, 2.Toyohashi Municipal Hospital, Department of Pediatrics, 3.Inflammation Pathology, Faculty of Medicine, Kagawa University, 4.Takamatsu Municipal Hospital, Department of Neurology)

The 91th Annual Meeting of JBS