[P-545] Synergic potentiation of LPS-HMGB1-indueced proinflammatory response by advanced glycation endproducts in macrophage

^○Shuji Mori¹, Masahiro Watanabe¹, Hidenori wake², Takashi Nishinaka², Omer F. Hatipoglu², Hideo Takahashi², Masahiro Nishibori³, Takao Toyomura¹ (1.Sch Pharm, Shujitsu Univ, 2.Fac Med, Kindai Univ, 3.Okayama Univ, Grad Sch Med Dent & Pharm Sci)

The 94th Annual Meeting of JBS

[P-546] N6-methyladenosine (m6A) is an endogenous A3 adenosine receptor ligand

^○Akiko Ogawa^1,2, Chisae Nagiri³, Wataru Shihoya³, Asuka Inoue¹, Kouki Kawakami¹, Suzune Hiratsuka¹, Junken Aoki^1,3, Yasuhiro Ito², Takeo Suzuki³, Tsutomu Suzuki³, Toshihiro Inoue², Osamu Nureki³, Kazuhito Tomizawa², Fan-Yan Wei^1,2 (1.Tohoku University, 2.Kumamoto University, 3.University of Tokyo)

The 94th Annual Meeting of JBS

[P-547] Presence and molecular forms of mitocryptide-3 related peptide in mtDAMPs

^○Yoshinori Sugimoto, Hiroki Morikawa, Takayuki Marutani, Yoshiaki Kiso, Hidehito Mukai (Labortory of Peptide Science, Graduate School of Bio-Science, Nagahama Institute of Bio-Science and Technology)

The 94th Annual Meeting of JBS

[P-548] Identification of the gut microenvironment by the cytokine reporter mice

^○Takahiro Hara (Institute for Frontier Life and Medical Sciences, Kyoto University)

The 94th Annual Meeting of JBS

[P-549] Halogen-bonding is not necessarily the reason of ERα-agonist and ERβ-antagonist bifunctional activities: ERα/ERβ-heterobifunctionality of hydrocarbon-group-containing next-generation bisphenols

^○Xiaohui Liu^1,2, Yutaka Matsuyama¹, Miki Shimohigashi^3,4, Yasuyuki Shimohigashi^1,4 (1.Dept. of Chem., Fac. of Sci., Kyushu Univ.,, 2.Dept. of Appl. Microb. Tech., Fac. of Biotech. and life Sci., Sojo Univ.,, 3.Lab. of Biol., Fac. of Sci., Fukuoka Univ.,, 4.Risk Science Project Lab.)

The 94th Annual Meeting of JBS

[P-550(3T13a-01)] Target DNA sequence-independent association of androgen receptor (AR) to the KLK3 (PSA) locus super enhancer

^○Takahiro Sawada^1,2, Koichi Nishimura^1,2, Yoshiaki Kanemoto^1,2, Jinichi Mori^1,2,3, Shigeaki Kato^1,2,4 (1.Research Institute of Innovative Medicine, Tokiwa Foundation, 2.Graduate School of Life Science and Engineering, Iryo Sosei University, 3.Department of Hematology, Jyoban Hospital, Tokiwa Foundation, 4.School of Medicine, Fukushima Medical University)

The 94th Annual Meeting of JBS

[P-551] Gene therapy and genome editing therapy for type 2 rickets model rats using adenoviral vector

^○Satoko Kise¹, Tadashi Okada^2,3, Kaori Yasuda¹, Miyu Nishikawa¹, Shinnichi Ikushiro¹, Yoshiaki Kanemoto², Shigeaki Kato^2,3, Tomoko Nakanihi⁴, Izumu Saito⁴, Toshiyuki Sakaki¹ (1.Toyama Prefectural University, 2.TOKIWA Research Institute of Innovative Medicine, 3.IRYO SOSEI UNIVERSITY community medical center, 4.Juntendo University medicine)

The 94th Annual Meeting of JBS

[P-552] Dual transcriptional activity of bisphenol C as ERα-agonists and ERβ-antagonists

Masaki Iwamoto, Takahiro Masuya, Mari Hosose, Koki Tagawa, Tomoka Ishibashi, ^○Ayami Matsushima (Dept. of Chem., Fac. of Sci., Kyushu Univ.)

The 94th Annual Meeting of JBS

[P-553] Tandem repeat sequence acting as a novel estrogen-responsive element in genome

^○Tomoka Ishibashi, Kyota Shirane, Mari Hosose, Kotone Ito, Ayami Matsushima (Dept. of Chem., Fac. and Grad. Sch. of Sci., Kyushu Univ.)

The 94th Annual Meeting of JBS

[P-554] Elucidation of the mechanism of nuclear structure formation by histone chaperone DEK

^○Shun Sawatsubashi¹, Koichi Nishimura¹, Toshio Matsumoto², Seiji Fukumoto¹ (1.Tokushima University, Institute of Advanced Medical Sciences, 2.Tokushima University, Fujii Mmorial Institute of Medical Sciences)

The 94th Annual Meeting of JBS