[P-735(1T14e-02)] Regulation of ferroptosis in glioblastoma cells

^○Yuki Ishimaru¹, Ikuo Kimura^1,2, Hironori Katoh^1,2 (1.Graduate School of Pharmaceutical Sciences, Kyoto University, 2.Graduate School of Biostudies, Kyoto University)

The 94th Annual Meeting of JBS

[P-736] Elucidation of molecular mechanism for intestinal tumorigenesis controlled by TMEPAI family

^○Naoko Nakano¹, Rei Hoshina¹, Yoshimi Uchida¹, Fumiko Itoh², Yukihide Watanabe³, Makoto Taketo⁴, Mitsuyasu Kato³, Susumu Itoh¹ (1.Laboratory of Biochemistry, Showa Pharmaceutical University, 2.Labotory of Stem Cells Regulation, Tokyo University of Pharmacy and Life Sciences, 3.Laboratory of Experimental Pathology, University of Tsukuba, 4.Medical Research Institute, Kitano Hospital)

The 94th Annual Meeting of JBS

[P-737] Development of a Simple Fluorescence Assay for Cystine Uptake via the xCT using Selenocystine.

^○Norio Hirakawa, Takashi Shimomura, Yuya Ohuchi, Munetaka Ishiyama (DOJINDO LABORATORIES)

The 94th Annual Meeting of JBS

[P-738] Activation of Nrf2 signal and chemoresistance by claudin-2 in spheroids of lung adenocarcinoma cells

Ayaka Ito¹, Haruka Nasako¹, Risa Akizuki¹, Yui Takashina¹, Yuta Yoshino¹, Satoshi Endo¹, Toshiyuki Matsunaga², ^○Akira Ikari¹ (1.Laboratory of Biochemistry, Gifu Pharmaceutical University, 2.Education Center of Green Pharmaceutical Sciences, Gifu Pharmaceutical University)

The 94th Annual Meeting of JBS

[P-739(1T14e-03)] linear ubiquitin chain-mediated tumor formation and progression

^○Katsuhiro Sasaki, Yoshie Hayamizu, Kazuhiro Iwai (Department of Molecular and Cellular Physiology, Graduate School of Medicine, Kyoto University)

The 94th Annual Meeting of JBS

[P-740] PRC2 insufficiency induces p53-dependent dyserythropoiesis in myelodysplastic syndrome through Cdkn2a de-repression

^○Kazumasa Aoyama^1,2, Daisuke Shinoda^1,2, Emi Suzuki², Yaeko Nakajima-Takagi^1,2, Motohiko Oshima^1,2, Shuhei Koide^1,2, Ola Rizq^1,2, Shiro Tara², Goro Sashida^2,3, Atsushi Iwama^1,2 (1.Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, 2.Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, 3.International Research Center for Medical Sciences, Kumamoto University)

The 94th Annual Meeting of JBS

[P-741] A transcription factor Zfp296, expressed in ES cells, causes cell tumorigenesis.

^○Yumi Mizoue¹, Tomomi Ikeda¹, Takako Ikegami¹, Koichi Hattori², Beate Heissig³, Hiroshi Koide¹ (1.Laboratory of Molecular and Biochemical Research, Research Support Center, Juntendo University Graduate School of Medicine, 2.Center of Genomic and Regeneration Medicine, Juntendo University Graduate School of Medicine, 3.Department of Immunological Diagnosis, Juntendo University Graduate School of Medicine)

The 94th Annual Meeting of JBS

[P-742] EZH2 controls neuroblastoma survival via actively regulates MYCN target genes without its methyltransferase activity

^○Shoma Tsubota, Kenji Kadomatsu (Department of Molecular Biology, Nagoya University Graduate School of Medicine)

The 94th Annual Meeting of JBS

[P-743] Blocking the ARF6-AMAP1 pathway cooperatively improves anti-PD-1 immunotherapy for pancreatic cancer

^○Ari Hashimoto¹, Haruka Handa¹, Soichiro Hata¹, Akio Tsutaho^1,2, Takao Yoshida³, Satoshi Hirano², Shigeru Hashimoto^1,4, Hisataka Sabe¹ (1.Dept. of Mol. Biol., Hokkaido Univ. Fac. of Med., 2.Dept. of Gastroent., Hokkaido Univ. Fac. of Med., 3.Res. Cent. of Onco., Ono Pharma.Co. Ltd., 4.Lab. of Immun. Reg., Immun. Front. Res. Cent.)

The 94th Annual Meeting of JBS

[P-744(1T14e-06)] The Dickkopf1 and FOXM1 positive feedback loop promotes tumor growth and associates with poor prognosis of pancreatic and esophageal cancer

^○Ryota Sada, Hirokazu Kimura, Naoki Takada, Hideki Yamamoto, Akira Kikuchi (Department of Molecular Biology and Biochemistry, Graduate School of Medicine, Osaka University)

The 94th Annual Meeting of JBS