[3PS7-1] PI 3-Kinase and Akt at the interface of signaling and metabolism

〇Alex Toker¹ (1.Harvard Medical School)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2016 1:04 PM - 1:46 PM

[3PS7-2] PH domain-only protein PHLDA3 is a novel p53-regulated repressor of Akt and a novel tumor suppressor of neuroendocrine tumors

〇Rieko Ohki¹ (1.National Cancer Center Research Institute)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2016 1:46 PM - 2:07 PM

[3PS7-3] Roles of Akt with its distinct binding partners

〇Masayuki Noguchi¹, Noriyuki Hirata¹, Futoshi Suizu¹ (1.Institute for Genetic Medicine, Div. Cancer Biology, Hokkaido Univ.)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2016 2:07 PM - 2:28 PM

[3PS7-4(3P-0376)] GIST and mast cell tumor require the PI3K-Akt pathway on intracellular compartments for their proliferation ~Oncogenic Kit signaling occurs selectively on the Golgi and endo/lysosomes~

〇Yuuki Obata¹, Keita Horikawa¹, Tsuyoshi Takahashi³, Yuki Akieda¹, Masahiko Tsujimoto⁴, Yasushi Hara¹, Hiroyasu Esumi², Toshirou Nishida⁵, Ryo Abe¹ (1.Div. of Immunobiol., RIBS, Tokyo Univ. of Sci., 2.Div. of Clin. Res., RIBS, Tokyo Univ. of Sci., 3.Dep. of Surgery, Grad. Sch. of Med., Osaka Univ., 4.Osaka Police Hospital, 5.NCC Hospital)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2016 2:28 PM - 2:49 PM

[3PS7-5(3P-0412)] Klf4-dose dependent metabolic shift through Tcl1-Akt activation in iPSC production

〇Ken Nishimura¹, Shiho Aizawa¹, Nugroho Fransiska Liliani¹, Yuta Sakuragi¹, Manami Ohtaka², Aya Fukuda¹, Mahito Nakanishi², Koji Hisatake¹ (1.Lab. of Gene Regulation, Fac. of Med., Univ. of Tsukuba, 2.Res. Inst. of Drug Discovery, AIST)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2016 2:49 PM - 3:10 PM

[3PS7-Conclusion] The PI3K-AKT signal transduction: update and future direction　

〇Masayuki Noguchi¹, Alex Toker² (1.Institute for Genetic Medicine, Div. Cancer Biology, Hokkaido Univ., 2.Harvard Medical School)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2016 3:10 PM - 3:15 PM

[3PS8-Introduction] Emerging gene therapy strategies from Japan.

〇Yasufumi Kaneda¹ (1.Osaka University)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2016 1:00 PM - 1:10 PM

[3PS8-1(3P-0836)] The front lines of the gene therapy using genome editing

〇Yumi Kanegae¹, Aya Maekawa², Mariko Suzuki², Izumu Saito², Saki Kondo² (1.Res.Cent. Med.Sci., Jikei Univ., 2.Mol.Gen., IMSUT, Univ. of Tokyo)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2016 1:10 PM - 1:35 PM

[3PS8-2] Gene therapy for AADC deficiency using Adeno-associate virus vector

〇Takanori Yamagata¹, Karin Kojima¹, Akihiko Miyauchi¹, Naoyuki Taga², Hiroaki Mizukami³, Mitsuhiro Kato⁴, Takeshi Nakajima⁵, Hitoshi Osaka¹, Shin-ichi Muramatsu^6,7 (1.Dept. Pediatr., Jichi Med. Univ., 2.Dept. anesthesiol, Jichi Med. Univ., 3.Div. Gene Therap., Jichi Med. Univ., 4.Dept. Pediatr., Showa Univ., 5.Dept. neurosurg., Jichi Med. Univ., 6.Dept. Neurol., Jichi Med. Univ., 7.Center Gene and cell therapy, Univ. of Tokyo)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2016 1:35 PM - 2:00 PM

[3PS8-3] Emerging gene therapy strategies from Japan.: Prostate cancer gene therapy

〇Yasutomo Nasu¹ (1.Dept.of Urol., Univ. of Okayama)

The 39th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 2, 2016 2:00 PM - 2:25 PM