[1P-0661] Alteration of ganglioside composition by medaka Neu3a decreases triglyceride accumulation in fish hepatocyte

〇Kazuki Oishi¹, Masaharu Komatsu^1,2, Kazuhiro Shiozaki^1,2 (1.Div. Biological Science and Technology, Unit. Grad. Sch. Agricult. Sci., Kagoshima Univ., 2.Div. Food Life Sciences, Fac. Fish, Kagoshima Univ.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1P-0662(2PW1-04-2)] Analysis of high meat diet-induced improvement mechanisms of tryacylglycerol metabolism by skatole, an intestinal bacteria metabolite.

〇KANA YUASA¹, KOUITHI KURATA⁵, RYOUSUKE TOMATSU², YASUTAKE TANAKA³, TAKUMA NOSE⁴, HIDEAKI KAWAHARA⁵, YUUTA WATANABE¹, KOUJI NISHIMURA⁴, MITSUO JISAKA⁴, KAZUNARI YOKOTA⁴, SATOSHI ISHIDUKA³, HIDEHISA SHIMIZU⁴ (1.Grad Sch of Nat Sci and Tech, Shimane Univ, 2.Fac of Life and Emviro Sci, Shimane Univ, 3.Res Fac of Agri, Hokkaido Univ, 4.Acad Assem, Shimane Univ, 5.Grad Sch of Life and Emviro Sci, Shimane Univ)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1P-0663] Oenocyte nuclear factors Seven-up/Samuel play crucial roles in lipid/sugar metabolism in the Drosophila third instar larvae

〇Airi Iwasawa¹, Hiroyuki Kose¹ (1.Dept. of NS, ICU)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1P-0664] The role of STARD10 and LPCAT1 in regulating lipid droplet formation in a nonalcoholic steatohepatitis (NASH) mouse model

〇Masanori Ito¹, Taichiro Tomida¹, Yoshinori Mikami¹, Daisuke Ohshima¹, Yoshikazu Takahashi², Hideo Shindou², Takao Shimizu², Satomi Adachi-Akahane¹ (1.Dept. of Physiol., Fac. Med., Toho Univ., 2.Dept. of Lipid Signaling, National Center for Global Health and Medicine)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1P-0665] Development of a diet-induced mouse model of NASH, and the effect of FABP1 repression on NASH pathology

〇Tatsuya Kusudo¹, Tamaki Takeuchi², Takako Mukai¹ (1.Faculty of Human Sci., Tezukayama Gakuin Univ., 2.Dept. of Biomed. Sci., Coll. of Life & Health Sci., Chubu Univ.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1P-0666] Inactivation of Sirtuin2 protects mice from acetaminophen-induced liver injury through the inhibition of S6K1 phosphorylation

〇Da Hyun Lee^1,2, Buhyun Lee^1,2, Jeong Su Park², Yu Seol Lee^1,2, Jin Hee Kim⁶, Yejin Cho², Yoonjung Jo³, Hyun-Seok Kim³, Yong-ho Lee^4,5, Ki Taek Nam^1,2, Soo Han Bae² (1.Brain Korea 21 PLUS Project for Medical Science, Yonsei University, 2.Severance Biomedical Science Institute, Yonsei Biomedical Research Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea, 3.Department of Bioinspired Science, Ewha Womans University, Seoul 120-750, Korea, 4.Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, 50-1, Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea, 5.Institute of Endocrine Research, Yonsei University College of Medicine, 50-1, Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea, 6.Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1P-0667] Gpnmb inhibits hepatic gluconeogenesis.

〇Yuto Ogushi¹, Yumika Ono¹, Yujiro Arimura¹, Takatomo Arai¹, Nobuhito Goda¹ (1.Department of life science & medical bioscience, school of advanced science and engineering, WASEDA university)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1P-0668] Liver regulates diet induced thermogenesis by controlling nardilysin

〇Hirotaka Iwasaki¹, Kiyoto Nishi³, Shintaro Matsuda², Mikiko Ohno¹, Eiichiro Nishi¹ (1.Dept of Pharmacol, Shiga Univ of Medical Science, 2.Dept of Cardiology, Univ of Kyoto, 3.Univ of Washington)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1P-0669] Lansoprazole protect against cisplatin-induced hepatic cytotoxicity through activation of Nrf2 pathway

〇Naoko Yamagishi¹, Yuta Yamamoto¹, Toshio Nishi¹, Takao Ito¹ (1.Dept. of Anatomy and Cell Biology, Wakayama Med. Univ. Graduate Sch. of Med.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1P-0670] Lobeglitazone, Antidiabetic drug, protects mice from lipogenesis-induced liver injury via inhibiting mTORC1

〇Yu Seol Lee^1,2, Jeong Su Park¹, Da Hyun Lee^1,2, Dong-Kyu Lee³, Sung Won Kwon^3,4, Byung-Wan Lee⁵, Soo Han Bae¹ (1.Severance Biomedical Science Institute, Yonsei Biomedical Research Institute, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea, 2.Brain Korea 21 PLUS Project for Medical Science, Yonsei University, 3.Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, 08826, Republic of Korea, 4.College of Pharmacy, Seoul National University, Seoul, 08826, Republic of Korea, 5.Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea)

The 41st Annual Meeting of the Molecular Biology Society of Japan