[2P-0511] α-Synuclein internalization into microglia is on the endocytic pathway by engagement of integrin α9β1.

〇Masumi Ito¹, Norihisa Nishimichi¹, Mikage Otani¹, Mari Harada¹, Yasuyuki Yokosaki^1,2 (1.Cell-Matrix Lab., Health Admin., Hiroshima Univ., 2.Clin. Gene., Hiroshima Univ. Hosp.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0512(1AW-04-5)] Acting out Nightmares: the molecular and neural mechanisms of REM sleep behavior disorder

〇Marina Takagi^1,2, Mitsuaki Kashiwagi^1,3, Mika Kanuka¹, Masashi Yanagisawa¹, Yu Hayashi¹ (1.International Institute for Integrative Sleep Medicine (WPI-IIIS), Univ of Tsukuba, 2.Master’s Prog of Med Sci, Univ of Tsukuba, 3.Doctoral Prog in Kansei, Univ of Tsukuba)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0513] Identification of a novel GBA mutation in Parkinson's disease and biochemical characterization of patient-derived lymphoblastoid cells

〇Yasuyo Suzuki¹, Ayaka Chikada ², Kimiko Katoh¹, Kenichiro Yamada¹, Daisuke Fukushi¹, Hiroyuki Ishiura², Kazushi Deguchi³, Jun Mitsui⁴, Shoji Tuji⁴, Nobuaki Wakamatsu⁵ (1.Dept of Genet, Inst for Develop Res, Aichi Human Serv Ctr, 2.Dept of Neurol, Univ of Tokyo, 3.Dept of Gastroenterol and Neurol, Faculty of Med, Kagawa Univ, 4.Dept of Mol Neurol, Univ of Tokyo, 5.Dept of Neurol, Neurol and Stroke Ctr, Takamatsu Municipal Hosp)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0514] Variation of intestinal bacterial flora and estimation of hydrogen production in Parkinson's disease patients

〇Mikako Ito¹, Tomonari Hamaguchi¹, Anzu Suzuki², Masaaki Hirayama², Kinji Ohno¹ (1.Neurogenetics, Nagoya University Graduate School of Medicine, 2.Pathophysiol. Lab. Sci., Nagoya University Graduate School of Medicine)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0515] Genetic interaction analysis of Parkinson's disease-associated genes that regulate membrane dynamics

〇Changxu Cui¹, Tsuyoshi Inoshita¹, Junyi Liu¹, Nobutaka Hattori^1,2, Yuzuru Imai^1,2 (1.Dept. of Parkinson's disease., Grad. Sch. of Med., Univ. of Juntendo, 2.Dept Neurol, Univ of Juntendo)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0516] In silico drug screening by using genome-wide association study (GWAS)-data repurposed a novel disease-modifying drug for Parkinson’s disease

〇TAKESHI UENAKA¹, WATARU SATAKE¹, Pei-Chieng Cha¹, HIDEKI HAYAKAWA², KOUSUKE BABA², SHIYING JIANG², KAZUHIRO KOBAYASHI¹, MOTOI KANAGAWA¹, YUKINORI OKADA^3,4, HIDEKI MOCHIZUKI², TATSUSHI TODA^5,1 (1.Div of Neurol/Mol Brain Sci, Kobe Univ Graduate School of Med, 2.Dep of Neurol, Osaka Univ Graduate School of Med, 3.Dep of Statistical Genetics, Osaka Univ Graduate School of Med, 4.Lab of Statistical Immunol, Immunol Frontier Research Center (WPI-IFReC), Osaka Univ, 5.Dep of Neurol, Graduate School of Med, The Univ of Tokyo)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0517] Screening for Parkin activation drug

〇Kahori Shiba¹, Tsuyoshi Inoshita¹, Yuzuru Imai², Nobutaka Hattori³ (1.Department of Treatment and Research in Multiple Sclerosis and Neuro-intractable Disease, Juntendo University Graduate School of Medicine, 2.Department of Research for Parkinson´s Disease, Juntendo University Graduate School of Medicine, 3.Department of Neurology, Juntendo University Graduate School of Medicine)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0518(2AW-08-6)] Dysregulated translation of localized RNA induced by cytoplasmic protein aggregation potentially leads to neurodegenerative disease

〇Kyota Yasuda¹ (1.Graduate School of Science, Hiroshima University)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0519] Role of Rab33 proteins in Spinocerebellar Ataxia 1 (SCA1) model mice

〇Joshua Chidiebere Mba¹, Yuichiro Ohishi¹, Akihiro Kato¹, Masashi Sogabe¹, Toshiaki Koda¹ (1.Grad Sch Life Sci, Hokkaido Univ)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[2P-0520] Screening of drugs conferring an increase in miRNA that is deficient in Huntington’s disease

〇Hideo Shimizu¹, Eri Suzuki¹, Masashi Fukuoka¹, Hirohiko Hohjoh¹ (1.Dept of Molecular Pharmacology, National Institute of Neuroscience, NCNP)

The 41st Annual Meeting of the Molecular Biology Society of Japan