[1P-0047] **Crystal structure of cf3-aequorin: a semi-synthetic aequorin with long half-decay time of luminescence**

〇Yuri Tomabechi¹, Satoshi Inouye², Takamitsu Hosoya³, Shun-ichi Sekine¹, Mikako Shirouzu¹ (1.RIKEN Center for Biosystems Dynamics Research, 2.JNC Co., 3.Tokyo Medical and Dental University)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1P-0048] Substrate binding mechanism of bacterial serine palmitoyltransferase

〇Aya Takahashi¹, Hiroko Ikushiro², Haruna Goto², Emi Ito³, Shinichi Ikushiro⁴, Yoshio Hirabayashi³, Takato Yano², Nobuo Kamiya^1,5, Ikuko Miyahara¹ (1.Grad School of Sci.,Osaka City Univ., 2.Dept. of Biochemistry, Osaka Med. College, 3.RIKEN Brain Science Inst., 4.Dept. of Biotechnology, Toyama Prefectural Univ., 5.OCARINA, Osaka City Univ.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1P-0049] Crystal Structure of Peptidyl-tRNA Hydrolase 2•Proteasomal Shuttle Protein Complex

〇Akihisa Ichimura¹, Kyoko Kasahara², Hirotatsu Imai¹, Yuji Uehara¹, Shuh-ichi Nishikawa², Toshio Uchiumi², Kosuke Ito² (1.Grad. Sch. of Sci. and Tech., Niigata Univ., 2.Dept. of Biol., Fac. of Sci., Niigata Univ.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1P-0050] Structural and functional analyses of the thymidylate synthase from Thermus thermophiles and the role of its C-terminal domain

〇Aoba Ogawa¹, Gen-ichi Sampei², Gota Kawai¹ (1.Fac. of Eng., Chiba Inst. of Tech., 2.Grad. Sch. of Inform. & Eng., The Univ. of Electro-Commun.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1P-0051] Cooperative domain formation by homologous motifs in HOIL-1L and SHARPIN plays crucial roles in LUBAC stabilization

〇Hiroaki Fujita¹, Akira Tokunaga², Masahiro Shirakawa², Kazuhiro Iwai¹ (1.Dept. of Mol. and Phys., Grad. Sch. of Med., Univ. of Kyoto, 2.Dept. of Mol. Eng., Grad. Sch. of Eng., Univ. of Kyoto)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1P-0052] The cofactor selection mechanism of SMAD2/3 in TGF-β signaling

〇Kenichi Miyazono¹, Saho Moriwaki¹, Yosuke Ohno¹, Hikaru Wada¹, Tomoko Ito¹, Akira Kurisaki^2,3, Makoto Asashima², Masaru Tanokura¹ (1.Dept of Appl Biol Chem, Grad Sch of Agr and Life Sci, The Univ of Tokyo, 2.BRD, AIST, 3.Grad Sch of Biol Sci, Nara Inst of Sci and Tech)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1P-0053] Single amino acid substitution drastically alters the structures and substrate specificities of restriction endonuclease

〇Keiko Kita¹, Yukio Watanabe¹, Bunzo Mikami¹ (1.Graduate School of Agriculture, Kyoto University)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1P-0054] Crystal structure of E.coli coli YidC at 2.8Å resolution reveals all cytoplasmic loops

〇Akiya Izumioka¹, Yoshiki Tanaka¹, Tomoya Tsukazaki¹ (1.NAIST)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1P-0055] Molecular dissection of CENP-A nucleosome recognition by CENP-C

〇Mariko Ariyoshi¹, Fumiaki Makino¹, Tomoki Sano¹, Reito Watanabe¹, Yasuhiro Arimura², Masatoshi Hara¹, Hitoshi Kurumizaka², Tetsuya Hori¹, Tatsuo Fukagawa¹ (1.Grad Sch of Front Biosci, Osaka Univ, 2.Dept of Biol Sci, Univ of Tokyo)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[1P-0056] Analysis of Tubulin Polymerization Promoting Protein family member 3

〇Kanji Yawata¹, Arashi Seki¹, Hiroshi Yoke¹, Chikako Shingyoji¹, Naohiro Kobayashi², Kyosuke Shinohara¹ (1.Tokyo University of Agriculture and Technology , 2.Institute for Protein Research, Osaka University)

The 41st Annual Meeting of the Molecular Biology Society of Japan