[3P-0578] Activation of innate immune pathways in a response to hematopoietic tumors and their suppression effect on the tumor growth in Drosophila mxc mutant larvae.

〇Suzuko Kinoshita¹, Mayo Araki¹, Yoshihiro H Inoue¹ (1.Dept. Insect Biomed. Res. Kyoto Inst. Tech.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[3P-0579] mTORC1 in osteoblastic niche controls acute myeloid leukemia progression

〇Kazuya Fukasawa¹, Tetsuhiro Horie¹, Manami Hiraiwa¹, Takanori Yamada¹, Takashi Iezaki¹, Katsuyuki Kaneda¹, Atsushi Hirao², Eiichi Hinoi¹ (1.Dept of Pharm Sci, Univ of Kanazawa, 2.Cancer Research insti, Univ of Kanazawa)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[3P-0580] Control of glioma progression by E3 ubiquitin ligase Smurf2

〇Manami Hiraiwa¹, Takashi Iezaki¹, Kazuya Fukasawa¹, Yuka Kitaguchi¹, Takanori Yamada¹, Katsuyuki Kaneda¹, Mitsutoshi Nakada², Atsushi Hirao³, Eiichi Hinoi¹ (1.Dept. of Pharm. Sci., Kanazawa Univ., 2.Dept. Neurosurgery, Kanazawa Univ., 3.Cancer Research Inst., Kanazawa Univ.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[3P-0581] Role of Fibulin2 splice variants in colon cancer

〇Ryo Funayama¹, Shingo Toyama¹, Wei-Chen Kao¹, Keiko Nakayama¹ (1.Grad. Sch. of Med., Tohoku Univ.)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[3P-0582] Roles of DIO2 (deiodinase, iodothyronine, type II) in colorectal cancer microenvironment

〇Masahiro Aoki¹, Teruaki Fujishita¹, Makoto Mark Taketo², Yasushi Kojima¹ (1.Divi of Pathophysiol, Aichi Cancer Ctr Res Inst, 2.Div of Exp Therapeutics, Kyoto Univ)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[3P-0583] Suppression of intestinal tumorigenicty in TMEPAI knockout mice

〇Keigo Sano¹, Teppei Shibasaki¹, Shoei Amano¹, Yutaro Yutaro¹, Ryo Ishikawa¹, Mana Itoh¹, Ai Konishi¹, Mami Ouchi¹, Yutaro Aoki¹, Miho Hiruma¹, Shiori Obokata¹, Fumiko Itoh², Yukihide Watanabe³, Makoto M Taketo⁴, Mitsuyasu Kato³, Susumu Itoh¹ (1.Lab of Biochem, Showa Pharm Univ, 2.Lab of Cardiovascular Med, Tokyo Univ of Pharm & Life Sci, 3.Dept of Exp Pathol, Comprehensive Human Sci, Univ of Tsukuba, 4.Dept of Pharmacology, Kyoto Univ Grad Sch of Med)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[3P-0584] Establishment of the mouse model of serrated adenocarcinoma of the colon by loss of CDX2 and BRAF^V600Emutation

〇Naoya Sakamoto¹, Takuya Hattori¹, Ririno Honma¹, Daiki Taniyama¹, Kaho Fukada¹, Kasuhiro Sentani¹, Naohide Oue¹, Eric Fearon², Wataru Yasui¹ (1.Hiroshima University, Dept. of Mol. Pathol , 2.Dept of Int. med, Pathol, Human Genetics, Univ. of Michigan)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[3P-0585] The Notch ligands Jag1 and Dll4 have opposing effects on hepatocellular carcinoma development

〇Yasuhiro Nakano^1,2, Katsuto Hozumi^1,3, Yutaka Inagaki^1,2 (1.Cent for Matrix Biol and Med, Grad Sch of Med, Tokai Univ, 2.Dept of Regen Med, Tokai Univ Sch of Med, 3.Dept of Immunol, Tokai Univ Sch of Med)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[3P-0586] Targeted next-generation sequencing of 50 cancer-related genes in Japanese patients with oral squamous cell carcinoma

〇Yasushi Sasaki^1,2, Takafumi Nakagaki^2,3, Miyuki Tamura², Masashi Idogawa², Kazuhiro Ogi³, Hiroyoshi Hiratsuka³, Takashi Tokino² (1.Biology, Sapporo Med Univ, 2.Med Genome Sci, Res Inst for Frontier Med, Sapporo Med Univ, 3.Dept of Oral Surgery, Sapporo Med Univ)

The 41st Annual Meeting of the Molecular Biology Society of Japan

[3P-0587] Tumoroid Never Knows? Tumoroids and Exosomes are New Hopes for Refractory Cancer Research and Therapeutics

〇Takanori Eguchi¹, Kisho Ono¹, Yuka Okusha¹, Toshifumi Fujiwara¹, Chiharu Sogawa¹, Stuart Calderwood² (1.Dept of Dent Pharmacol, Okayama Univ, 2.Harvard Med Sch)

The 41st Annual Meeting of the Molecular Biology Society of Japan