[2P-0090] Epigenetic and transcriptomic characterization of spermatogonial stem cell differentiation

〇Shin-ichi Tomizawa¹, Yuki Kobayashi¹, Antoine H.F.M. Peters³, Konstantinos Anastassiadis⁴, A Francis Stewart⁴, Masahide Seki², Yutaka Suzuki², Stephen Clark⁵, Gavin Kelsey⁵, Kazuyuki Ohbo¹ (1.Histol. Cell. Biol., Yokohama City Univ. Sch. of Med., 2.Dept. of Comput. Biol. and Med. Sci., Grad. Sch. of Front. Sci., Univ. of Tokyo, 3.Friedrich Miescher Inst. for Biomed. Res., 4.Biotech. Ctr., Ctr. for Mol. and Cell. Bioeng., Tech. Univ. Dresden, 5.Epigenetics, Babraram Inst.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[2P-0091] In-silico Identification of Spatio-Temporal Histone Modifications Associated with Regulation for Fate Decision and Differentiation of Adipose-derived Stem Cells

〇Yukiyo Yamatani¹, Sung-Joon Park², Kenta Nakai³ (1.Grad. Sch. Front. Sci., U. Tokyo, 2.Inst. Med. Sci., U. Tokyo, 3.Grad. Sch. Front. Sci., U. Tokyo & Inst. Med. Sci., U. Tokyo)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[2P-0092] AKT signaling promotes epigenetic reprogramming through transcriptional and metabolic shift during iPSC generation

〇Yoichi Sekita¹, Yuki Sugiura², Akari Matsumoto¹, Yuki Kawasaki³, Toshiaki Ito¹, Kazuya Akasaka¹, Terushi Yamazaki¹, Ryo Konno⁴, Toshinobu Nakamura⁵, Fumitoshi Ishino³, Yoshio Kodera^4,6, Takashi Kohda^3,7, Tohru Kimura¹ (1.Lab. of Stem Cell Biol., Dept. of Biosci., Kitasato Univ. Sch. of Sci., 2.Dept. of Biochem. & Integrative Med. Biol., Sch. of Med., Keio Univ., 3.Dept. of Epigenetics, Med. Res. Inst., TMDU, 4.Dept. of Phys., Kitasato Univ. Sch. of Sci., 5.Lab. of Epigenetic Regulation, Nagahama Inst. of Biosci. and Tech., 6.Cent. for Disease Proteomics, Kitasato Univ. Sch. of Sci., 7.Lab. of Embryol. & Genomics, Dept of Biotech., Univ. of Yamanashi)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[2P-0093] A heterozygous K36M mutation in histone H3.3 affects chondrocyte differentiation and limb development

〇Shusaku Abe¹, Takashi Ishiuchi¹, Hiroyuki Sasaki¹ (1.Div. of Epigenomics, MIB, Kyushu Univ. )

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[2P-0094] Evaluation of the usefulness of saliva for DNA methylation analysis in cohort studies

〇Ayaka Fujii¹, Yui Murata¹, Sho Kanata^2,3, Shinya Fujikawa², Tempei Ikegame², Yutaka Nakachi¹, Zhilei Zhao^2,4, Seiichiro Jinde², Kiyoto Kasai^2,4, Miki Bundo^1,5, Kazuya Iwamoto¹ (1.Dept. of Molbrain, Grad. Sch. of LifeScience, Kumamoto Univ., 2.Dept. of Psychiatry, Grad. Sch. of Med., Univ. of Tokyo, 3.Dept. of Psychiatry, Sch. of Med., Univ. of Teikyo, 4.Int. Res. Center for Neurointelligence, Univ. of Tokyo, 5.JST PRESTO)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[2P-0095] Local assembly of chromatin at the transcription start site is inversely correlated to the level of transcription

〇Satoru Ishihara¹, Yohei Sasagawa², Takeru Kameda^2,3, Hayato Yamashita⁴, Naoe Kotomura¹, Masayuki Abe⁴, Yohei Shimono¹, Itoshi Nikaido² (1.Fujita Health Univ. Sch. Med., 2.RIKEN Center Biosyst. Dynam. Res., 3.Hiroshima Univ. Grad. Sch. Sci., 4.Osaka Univ. Grad. Sch. Eng. Sci.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[2P-0096] Identification of pioneer transcription factors from DNA methylation profiles

Shuhei Noguchi¹, Yurina Miyajima¹, Takahiro Suzuki^1,2, Yuki Tanaka^1,2, Jing-Ru Li¹, Hajime Nishimura¹, Mami Kishima¹, Takeya Kasukawa¹, 〇Harukazu Suzuki¹ (1.RIKEN IMS, 2.Yokohama City Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[2P-0097] Role of histone methylation in guiding DNA methylation in the male germline

〇Kenjiro Shirane¹, Fumihito Miura², Takashi Ito², Matthew C Lorincz¹ (1.Dept. of Medical Genetics, UBC, 2.Dept. of Biochem., Grad. Sch. of Med. Sci., Kyushu Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[2P-0098] Atypical DNA methylation defects of ICR1 cause two opposite imprinting disorders, Beckwith-Wiedemann syndrome and Silver-Russell syndrome

〇Hidenobu Soejima¹, Feifei Sun^1,2, Yuka Tanoue¹, Hitomi Yatsuki¹, Ken Higashimoto¹ (1.Div. of Mol. Genet. & Epigenet., Dept. of Biomol. Sci. Fac. of Med., Saga Univ., 2.Dept.of Ultrasound, Shengjing Hosp. of China Med. Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[2P-0099] Comprehensive DNA methylation analysis of imprinted DMRs in Sotos syndrome reveals IGF2 -DMR0 as a DNA methylation-dependent, P0 promoter-specific enhancer

〇Ken Higashimoto¹, Hidetaka Watanabe^1,2, Noriko Miyake³, Sumiyo Morita⁴, Takuro Horii⁴, Izuho Hatada⁴, Naomichi Matsumoto³, Hidenobu Soejima¹ (1.Div. of Mol. Genet. & Epigenet., Dept. of Biomol. Sci., Fac. of Med., Saga Univ., 2. Dept. of Plastic & Reconstructive Surgery, Saga Univ. Hosp., 3.Dept. of Hum. Genet., Yokohama City Univ. Grad. Sch. of Med., 4.Lab. of Genome Sci., Biosig. Genome Resource Ctr., Inst. for Mol. and Cell. Reg., Gunma Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan