[3AW-06-4] Discovery of Aldehyde Degradation Deficiency (ADD) Syndrome: a novel Fanconi anemia-like Bone Marrow Failure disorder caused by solely metabolic deficits

^○Anfeng Mu¹, Asuka Hira¹, Akira Niwa², Mitsujiro Osawa², Minako Mori¹, Yusuke Okamoto¹, Megumu Saito², Minoru Takata¹ (1.Radiat. Biol. Cent., Grad. Sch. of Biostudies, Kyoto University, 2.CiRA, Kyoto University)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 3, 2021 9:51 AM - 10:07 AM

[3AW-06-5] RFWD3 is required for PCNA modification-dependent DNA damage tolerance in human cells

^○Rie Kanao^{1, 2}, Hidehiko Kawai³, Toshiyasu Taniguchi⁴, Minoru Takata⁵, Chikahide Masutani^{1, 2} (1.Res. Inst. Environ. Med., Nagoya Univ., 2.Nagoya Univ. Grad. Sch. Med., 3.Grad. Sch. Biomed. Health Sci., Hiroshima Univ., 4.Tokai Univ. Sch. Med., 5.Rad. Biol. Center, Grad. Sch. Biostudies, Kyoto Univ.)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 3, 2021 10:07 AM - 10:23 AM

[3AW-06-6] Control of genome integrity by remove the PCNA from chromatin

^○Yasushi Shiomi, Asuka Tadokoro, Hideo Nishitani (Grad. Sch. of Science, Univ. of Hyogo)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 3, 2021 10:23 AM - 10:39 AM

[3AW-06-7] Chromatin remodeling in maintenance DNA methylation and chromosome stability: Insights from ICF syndrome studies

^○Motoko Unoki, Hiroyuki Sasaki (Div. Epi. & Dev., Med. Inst. Bioreg., Kyushu Univ.)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 3, 2021 10:39 AM - 10:55 AM

[3AW-06-8] Analysis of nicks-induced genome mutations and its application to genome editing

^○Shinichiro Nakada^{1, 2}, Akiko Tomita² (1.Co-creat, Osaka Univ., 2.Sch. Med. Osaka Univ.)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 3, 2021 10:55 AM - 11:11 AM

[3AW-07-1] Different roles of catalytic subunits in the CCR4-NOT deadenylase complex

^○Toru Suzuki¹, Takumi Tomohiro², Chisato Kikuguchi¹, Akira Fukao², Toshinobu Fujiwara², Tadashi Yamamoto³ (1.RIKEN, 2.Kindai Univ., 3.OIST)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 3, 2021 9:02 AM - 9:16 AM

[3AW-07-2] Dissecting RNA-regulatory network orchestrated by CCR4-NOT complex in cardiovascular diseases

^○Keiji Kuba (Dept. of Biochem. Met. Sci., Akita Univ. Grad. Sch. of Med.)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 3, 2021 9:16 AM - 9:31 AM

[3AW-07-3] Physiological impacts of Arabidopsis deadenylases and Pumilio RNA binding proteins, that are component of the AtCCR4-NOT complex

Sota Kurachi¹, Riko Imahori¹, Toshihiro Arae², Misato Ohtani², ^○Yukako Chiba^{1, 3} (1.Grad.Sch. Life Sci. Hokkaido Univ., 2.Grad.Sch.Front.Sci.Univ.Tokyo, 3.Fac. Sci. Hokkaido Univ.)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 3, 2021 9:31 AM - 9:46 AM

[3AW-07-4] An RNA-binding protein Quaking safeguards motor neuron function through pre-mRNA processing

^○Masato Yano^{1, 2}, Yoshika HayakawaYano^{1, 2} (1.Div of Neurobiol and Anat, Niigata Univ Grad Sch of Med and Dent Sci,, 2.Dept of Physiol, Keio Univ Sch of Med)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 3, 2021 9:46 AM - 10:05 AM

[3AW-07-5] Contribution of neuronal RNA G-quadruplex structures to cellular phase separation

^○Sefan Asamitsu¹, Moe Kawasaki², Yuki Hirose³, Yasushi Yabuki^{1, 2}, Gengo Kashiwazaki⁴, Anandhakumar Anandhakumar⁵, Toshikazu Bando³, Hiroshi Sugiyama^{3, 6}, Norifumi Shioda^{1, 2} (1.IMEG, Kumamoto Univ., 2.Grad. Sch. of Pharm. Sci., Kumamoto Univ., 3.Grad. Sch. of Sci., Kyoto Univ., 4.Grad. Sch. of Agric., Kindai Univ., 5.Univ. of Oxford, 6.iCeMS, Kyoto Univ.)

The 44th Annual Meeting of the Molecular Biology Society of Japan |Fri. Dec 3, 2021 10:05 AM - 10:17 AM