[P2-175] High b value DWI for the detection of bright tree appearance in AESD
[Introduction]
The bright tree appearance (BTA) on diffusion-weighted imaging (DWI) is essential for the diagnosis of acute encephalopathy with biphasic seizures and late reduced diffusion (AESD). High b value DWI has been reported to improve detection rates for CNS lesions, including ischemia. We evaluated the usefulness of high b value (b=3000s/mm2) compered with the conventional b value (b=1000s/mm2) DWI for the detection of BTA.
[Patients and methods]
Five patients with AESD (4 boys and 1 girl, average age of 2.4 years) were enrolled in this study. With a 3 tesla MRI, we assessed BTA on DWI with b=1000 and 3000 in each lobe (bilateral frontal, parietal, temporal, occipital lobes and insular) by using a BTA score (2 point, clear BTA; 0 point, no BTA; 1 point, ambiguous BTA or less clear BTA when both DWI showed BTA).
[Results]
The BTA score with b=3000 is higher than that of b=1000 in 3 patients (b=3000/b=1000 score: 6/0, 4/1, 6/3). In 2 patients, the BTA score with b=3000 is same as that of b=1000 (b=3000/b=1000 score: 12/12, 16/16).
[Conclusions].
High b value DWI can improve visualizing of BTA compared with the conventional DWI, which may be useful for the early diagnosis of AESD.
The bright tree appearance (BTA) on diffusion-weighted imaging (DWI) is essential for the diagnosis of acute encephalopathy with biphasic seizures and late reduced diffusion (AESD). High b value DWI has been reported to improve detection rates for CNS lesions, including ischemia. We evaluated the usefulness of high b value (b=3000s/mm2) compered with the conventional b value (b=1000s/mm2) DWI for the detection of BTA.
[Patients and methods]
Five patients with AESD (4 boys and 1 girl, average age of 2.4 years) were enrolled in this study. With a 3 tesla MRI, we assessed BTA on DWI with b=1000 and 3000 in each lobe (bilateral frontal, parietal, temporal, occipital lobes and insular) by using a BTA score (2 point, clear BTA; 0 point, no BTA; 1 point, ambiguous BTA or less clear BTA when both DWI showed BTA).
[Results]
The BTA score with b=3000 is higher than that of b=1000 in 3 patients (b=3000/b=1000 score: 6/0, 4/1, 6/3). In 2 patients, the BTA score with b=3000 is same as that of b=1000 (b=3000/b=1000 score: 12/12, 16/16).
[Conclusions].
High b value DWI can improve visualizing of BTA compared with the conventional DWI, which may be useful for the early diagnosis of AESD.