Academic Program [Oral A]

17. Biofunctional Chemistry, Biotechnology » Oral A

[D1441-1am] 17. Biofunctional Chemistry, Biotechnology

Wed. Mar 22, 2023 9:00 AM - 11:40 AM D1441 (1441, Bldg. 14 [4F])

Chair: Kazuya Matsuo, Takashi Sakamoto

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9:20 AM - 9:30 AM

[D1441-1am-01] Development of Theranostics Technology by Using Radiohalogens- Development of nucleophilic ¹⁸F fluorination using benzenesulfonyloxy groups with electron withdrawing substituent.

^○Shogo Iida¹, Tetsuto Tago², Jun Toyohara², Hiroshi Tanaka¹ (1. Tokyo Institute of Technology, 2. Tokyo Metropolitan Geriatric Medical Center)

[Lang.] Japanese

9:30 AM - 9:40 AM

[D1441-1am-02] Development of Theranostics Technology by Using Radiohalogens- Synthesis of ¹²⁵I-Labeled Activated Esters possessing a Neopentyl-Labeling Group

^○Masatoshi Tada¹, Yuta Kaizuka², Tomoya Uehara², Hiroshi Tanaka¹ (1. Tokyo Institute of Technology, 2. Chiba University)

[Lang.] Japanese

9:40 AM - 9:50 AM

[D1441-1am-03] Investigation for effects of the position of OH groups on the reaction mechanism of O₂^-・ and benzenetriols

Rumi Kobata¹, Kouki Tsuchiya¹, Ryota Nakano¹, ^○Yusuke Miyake¹, Kunihiko Tajima¹, Kenji Kanaori¹ (1. Kyoto Institute of Technology)

[Lang.] Japanese

9:50 AM - 10:00 AM

[D1441-1am-04] Control of mitotic cell division using the photoswitchable covalent inhibitor targeting CENP-E

^○Kazuya Matsuo¹, Shusuke Yamaoka¹, Tomonori Waku¹, Akio Kobori¹ (1. Kyoto Institute of Technology)

[Lang.] Japanese

Break (10:00 AM - 10:10 AM)

10:10 AM - 10:20 AM

[D1441-1am-05] Development of a method for simultaneous measurement of multiple factors in the intracellular local environment

^○Yuya Shibano¹, Zhang Zhengxiao¹, Eiji Nakata¹, Takashi Morii¹, Hisaaki Hirose², Shiro Hutaki² (1. Institute of advanced energy, Kyoto University, 2. Institute for Chemical Research, Kyoto University)

[Lang.] Japanese

10:20 AM - 10:30 AM

[D1441-1am-06] Development of Dual-responsive Photoluminescent Probe for Detection of Enzyme Activity and Reactive Oxygen Species

^○Kohei Takayama¹, Ayako Suzuki¹, Huo Wenting¹, Takashi Morimoto¹, Huiying Mu¹, Koji Miki¹, Ohe Koichi¹ (1. Kyoto university)

[Lang.] Japanese

10:30 AM - 10:40 AM

[D1441-1am-07] Development of cyanine dyes for identification of aldehyde dehydrogenase isoforms

^○Koki Miki¹, Daiki Yamanaka¹, Huiying Mu¹, Koji Miki¹, Kouichi Ohe¹ (1. Kyoto University)

[Lang.] Japanese

10:40 AM - 10:50 AM

[D1441-1am-08] Development of Water-soluble pH-Responsive Cyanine Dyes Containing Anionic Substituents

^○Shuai Shao¹, Huiying Mu¹, Koji Miki¹, Kouichi Ohe¹ (1. Kyoto University)

[Lang.] Japanese

Break (10:50 AM - 11:00 AM)

11:00 AM - 11:10 AM

[D1441-1am-09] Regulating the binding selectivity of dual-color fluorescence switch-on probe that responses with duplex and quadruplex DNA

Yuka Muraoka¹, Yu Yasuhara², Marina Iwai², ^○Takashi Sakamoto^1,2 (1. Grad. Sch. Systems Eng., Wakayama Univ., 2. Faculty of Systems Eng., Wakayama Univ.)

[Lang.] Japanese

11:10 AM - 11:20 AM

[D1441-1am-10] The promotion of expression of gene that causes triplet repeat disease using repeat-targeting DNA binding molecule

^○Junnosuke Hatanaka¹, Toshikazu Bando¹, Hiroshi Sugiyama² (1. Graduate school of Science, Kyoto University, 2. Institute for Integrated Cell-Material Sciences, Kyoto University)

[Lang.] Japanese

11:20 AM - 11:30 AM

[D1441-1am-11] Comparing the Properties of DNA-Binding Pyrrole−Imidazole Polyamides with Different Structures (Linear versus Cyclic)

^○Yuki Hirose¹, Huy N. Hoang², Kaori Hashiya¹, Toshikazu Bando¹, Hiroshi Sugiyama³, David P. Fairlie² (1. Graduate School of Science, Kyoto University, 2. Institute for Molecular Bioscience, The University of Queensland, 3. Institute for Integrated Cell-Material Science (WPI-iCeMS), Kyoto University)

[Lang.] English

11:30 AM - 11:40 AM

[D1441-1am-12] Synthesis and Evaluation of Pyrrole-Imidazole Polyamide Conjugates with Pyridostatin Analogs

^○Mitsuharu Ooga¹, Toshikazu Bando¹, Hiroshi Sugiyama² (1. Kyoto University Graduate School, 2. Institute for Integrated Cell-Material Sciencies, Kyoto University)

[Lang.] Japanese

Session information

[D1441-1am] 17. Biofunctional Chemistry, Biotechnology

[D1441-1am-01] Development of Theranostics Technology by Using Radiohalogens- Development of nucleophilic ¹⁸F fluorination using benzenesulfonyloxy groups with electron withdrawing substituent.

[D1441-1am-02] Development of Theranostics Technology by Using Radiohalogens- Synthesis of ¹²⁵I-Labeled Activated Esters possessing a Neopentyl-Labeling Group

[D1441-1am-03] Investigation for effects of the position of OH groups on the reaction mechanism of O₂^-・ and benzenetriols

[D1441-1am-04] Control of mitotic cell division using the photoswitchable covalent inhibitor targeting CENP-E

[D1441-1am-05] Development of a method for simultaneous measurement of multiple factors in the intracellular local environment

[D1441-1am-06] Development of Dual-responsive Photoluminescent Probe for Detection of Enzyme Activity and Reactive Oxygen Species

[D1441-1am-07] Development of cyanine dyes for identification of aldehyde dehydrogenase isoforms

[D1441-1am-08] Development of Water-soluble pH-Responsive Cyanine Dyes Containing Anionic Substituents

[D1441-1am-09] Regulating the binding selectivity of dual-color fluorescence switch-on probe that responses with duplex and quadruplex DNA

[D1441-1am-10] The promotion of expression of gene that causes triplet repeat disease using repeat-targeting DNA binding molecule

[D1441-1am-11] Comparing the Properties of DNA-Binding Pyrrole−Imidazole Polyamides with Different Structures (Linear versus Cyclic)

[D1441-1am-12] Synthesis and Evaluation of Pyrrole-Imidazole Polyamide Conjugates with Pyridostatin Analogs

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