[27B2-pm] Synthesis 7 (Others)

Mon. Mar 27, 2023 3:50 PM - 5:26 PM [Room B2] Institute for the Advancement of Higher Education: N2 (Bldg. N: 1F)

Chair: Tsubasa Inokuma, Naoyuki Toriumi

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3:50 PM - 4:02 PM

[27B2-pm11] Post-cleavable PCR primer aiming the cellular build-up regulated by photo-irradiation

○Haruka Hiraoka¹, Hirotaka Murase^1,2, Naoko Abe¹, Yuki Yoshida¹, Fumitaka Hashiya¹, Hiroshi Abe¹ (1. Grad. Sch. Sci., Nagoya Univ., 2. Dept. Pharm., Nagasaki Int. Univ.)

4:02 PM - 4:14 PM

[27B2-pm12S] Development of uridine-selective cross-linkable 2-amino-7-deaza-6-vinylpurine deoxyriboside toward miRNA inhibition

○Nadya Soemawisastra^1,2, Hidenori Okamura^1,2, Ahmed Abdelhady^1,2, Kazumitsu Onizuka^1,2, Mamiko Ozawa¹, Fumi Nagatsugi^1,2 (1. IMRAM, Tohoku Univ., 2. Grad. Sch. Sci., Tohoku Univ.)

4:14 PM - 4:26 PM

[27B2-pm13S] **Synthesis and evaluation of in vitro and in vivo properties of ASOs conjugated with divalent PEGs**

○TAHIA TAUFIQ^1,2, Taslima Rahman Chowdhury^1,2, Md Ariful Islam¹, Yuuya Kasahara^1,2, Taisuke Nakayama², Haruhiko Kamada², Takashi Osawa¹, Satoshi Obika^1,2,3 (1. Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan, 2. National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), 7-6-8 Saito-Asagi, Ibaraki, Osaka 567-0085, Japan, 3. Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University, 1-3 Yamadaoka, Suita, Osaka 565-0871, Japan)

4:26 PM - 4:38 PM

[27B2-pm14S] Development of Tryptophane-oriented sulfenylation via thioether

○Hayate Shida¹, Akihiro Taguchi¹, Yuma Tokita¹, Yan Cui¹, Reo Kishi¹, Sho Konno¹, Atsuhiko Taniguchi¹, Yoshio Hayashi¹ (1. Sch. Pharm., Tokyo Univ. of Pharm. and Life Sci.)

4:38 PM - 4:50 PM

[27B2-pm15S] Effect of N-o-Nitrobenzylation on Conformation and Membrane Permeability of Linear Peptides

○Zhihan Huang¹, Yuko Otani¹, Tomohiko Ohwada¹ (1. Grad. Sch. Pharm. Sci., Tokyo Univ.)

4:50 PM - 5:02 PM

[27B2-pm16S] Metal-Free Synthesis of Acyl Glycosides and Application to Oligosaccharide Synthesis

○KANA YANASE¹, KOJI MORIMOTO^1,2, TETSUYA KAJIMOTO^1,2, KITA YASUYUKI² (1. Grad. Sch. Pharm. Sci., Ritsumeikan Univ., 2. Res. Org. Sci and Tech., Ritsumeikan Univ.)

5:02 PM - 5:14 PM

[27B2-pm17S] Atroposelective N-acylation of 1,5-benzodiazepinones by introduction of central chirality

○Kaoru Funaki¹, Hidetsugu Tabata¹, Yusuke Nakazato¹, Yuka Takahashi¹, Tomohiko Tasaka², Hideyo Takahashi³, Hideaki Natsugari^2,4, Tetsuta Oshitari¹ (1. Faculty of Pharma Sciences, Teikyo Univerisity, 2. Affinity Science Corporation, 3. Faculty of Pharmaceutical Sciences, Tokyo University of Science, 4. Graduate School of Pharmaceutical Sciences, The University of Tokyo)

5:14 PM - 5:26 PM

[27B2-pm18S] Electrochemical synthesis of helicenes, dehydrohelicenes, and circulenes

○Ahmed Sabri¹, Mohamed S. H. Salem¹, Md. Imrul Khalid¹, Masaru Kondo³, Makoto Sako², Hiroaki Sasai², Shinobu Takizawa¹ (1. SANKEN, Osaka Univ., 2. Grad. Sch. Pharm. Sci., Osaka Univ., 3. Grad. Sch. Sci. Eng., Ibaraki Univ.)

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