[2E01-04] Radiation Medicine 1

[2E03] Effect of Blood Flow for Combination of Hyperthermia with Radiation Therapy for Treatment in Breast Tumor

*Alexa Barrios¹, Oiendrila B Debnath¹, Malvina Supper¹, Koichi Ito², Kazuyuki Saito², Mitsuru Uesaka¹ (1. Univ. of Tokyo, 2. Chiba Univ.)

Keywords:hyperthermia, radio-resistent

Hyperthermia combined with subsequently applied radiation can be effective for treatment of tumors. By increasing the temperature, tumors become radiosensitive, resulting in the ability to reduce the radiation dose. Blood flow, however, is an important factor which impacts the overall hyperthermia process. During heat exposure, tumor temperature rises higher since heat dissipation by blood flow is slower in tumors than in normal tissues due to the vascular structure of the tumor. Therefore, the aim of this study is to consider the effect of blood flow in simulation and dynamic phantoms for the combination therapy.