2018 Annual Meeting

Presentation information

Oral presentation

II. Radiation, Accelerator and Beam Technologies » 202-2 Radiation Physics, Radiation Detection and Measurement

[3H01-05] Analyzing Technique

Wed. Mar 28, 2018 9:30 AM - 10:50 AM Room H (U2-213 -U2 Building)

Chair: Masashi Takada (National Defense Academy of Japan)

9:45 AM - 10:00 AM

[3H02] Development of Analytical Method for 14C Determination in Biomedical Sample by Mid-IR Cavity Ring-down Spectroscopy (3)

*Ryohei Terabayashi1, Volker Sonnenschein1, Hideki Tomita1, Noriyoshi Hayashi1, Lei Jin1, Masahito Yamanaka1, Norihiko Nishizawa1, Atsushi Sato2, Kenji Yoshida2, Tetsuo Iguchi1 (1. Nagoya Univ., 2. Sekisui Medical Co., Ltd. Drug Development Solutions Center)

Keywords:14C, Trace isotope analysis, Laser spectroscopy

医薬品開発領域におけるヒト薬物動態試験に向けて、中赤外レーザーを用いたキャビティーリングダウン分光に基づく14C分析法の開発を進めている。今回は分析システムの感度の向上、および動物薬物動態評価の実証実験について報告する。