[P1-186] Early onset brain calcification is a risk factor for hypocalcemia after calcium supplement treatment in children with parathyroid disorders
[Introduction] Parathyroid disorders can lead to severe complications, such as epilepsy and kidney dysfunction, and the severity of these diseases are always associated with the development of hypocalcemia. A reliable predictor for hypocalcemia will allow early intervention and therapy adjustment to reach optimal prognosis. We examined the role of early onset brain calcification as a predictor of hypocalcemia after treatment. [Method] In this case-control study, we retrospectively reviewed the consecutive patients with results of CT scan after diagnosis who have achieved convulsion free after treatment. The severity of brain calcifications in CT scan and the total calcium level after convulsion free were recorded. [Results] We reviewed 57 patients with parathyroid disorders, and 30 of them are children. In child patient, early onset brain calcifications is a predictor of hypocalcemia after treatment, with sensitivity, specificity to be 94.74% and 54.55%, respectively. [Conclusion] We found that early onset brain calcifications is predictive of hypocalcemia after treatment. Routine assay of this rule could be used, as it could prompt early intervention and treatment adjustment to avoid severe complications.