[P1-34] Probable etiology of mild encephalopathy with reversible isolated lesions in the corpus callosum in children: A review of 20 cases
[Objective] To explore the etiological spectrum of solitary corpus callosum lesions in children.
[Materials and Methods] Retrospective analysis of clinical and laboratory features and brain MRI images of 20 cases in children, who suffered from the isolated corpus callosum lesions and treated in our unit between January,2011 and April, 2014.
[Results] The relative impact of risk factors based on our research included suspected viral encephalitis, convulsions, and rotavirus. The average age of onset was 3.64±3.25 years old. The most prevalent disorders were seizures (13cases，65%), fever (10cases，50%), and gastrointestinal symptoms with vomiting or diarrhea(10cases，50%). Then positive stiff neck (5cases，25%), fatigue (6cases，30%,) headache (2cases，10%), altered states of consciousness (4cases，20%); Corpus callosum followed up for the shortest duration of 12 days, and the longest 51 days, with an average of 29.5 ± 10.28 days. Brain magnetic resonance image showed the splenium of the corpus callosum (SCC) isolated oval lesions, low signal on T1 weighted images and ADC images, high signal on T2 weighted images and DWI images at onset.
[Conclusions] The cause of the disease may be associated with mild encephalitis, convulsions, viral infections, and diarrhea.
[Materials and Methods] Retrospective analysis of clinical and laboratory features and brain MRI images of 20 cases in children, who suffered from the isolated corpus callosum lesions and treated in our unit between January,2011 and April, 2014.
[Results] The relative impact of risk factors based on our research included suspected viral encephalitis, convulsions, and rotavirus. The average age of onset was 3.64±3.25 years old. The most prevalent disorders were seizures (13cases，65%), fever (10cases，50%), and gastrointestinal symptoms with vomiting or diarrhea(10cases，50%). Then positive stiff neck (5cases，25%), fatigue (6cases，30%,) headache (2cases，10%), altered states of consciousness (4cases，20%); Corpus callosum followed up for the shortest duration of 12 days, and the longest 51 days, with an average of 29.5 ± 10.28 days. Brain magnetic resonance image showed the splenium of the corpus callosum (SCC) isolated oval lesions, low signal on T1 weighted images and ADC images, high signal on T2 weighted images and DWI images at onset.
[Conclusions] The cause of the disease may be associated with mild encephalitis, convulsions, viral infections, and diarrhea.