[P1-58] Characteristics of the focal clinical manifestation and Electroencephalogram in children with typical absence seizure
Objective To investigate the correlation among the focal clinical manifestation，ictal and interictal Electroencephalogram (EEG) features in children with typical absence seizure. Methods The clinical manifestations of the attacks, ictal and interictal EEG change were retrospectively analyzed in 34 cases of children with typical absence seizure from 2012 to 2016 in our hospital neurologist clinics. All of the cases have completed the video EEG monitoring (0.5-1 hour). Results Typical absence seizure were all observed in 34 cases, and absence seizure accompanied by focal clinical manifestations were detected in 3 cases: 1 case showed eyes gazed to the left; 1 case showed the head and body turned right, and the right side of the body presented involuntary movement; 1 case showed eyes blinked, head turned back, right upper limb rhythmic wobbled, and left hand groped. 30 cases manifested one or more of the performances, such as reduced alertness or responsiveness, nictation, making clicks, bend or look up, body shaking, neck rhythmic clonus or double lower limbs rhythmic clonus, and kneading eyes. 33 cases showed visible focal starting (former head or occipital region) at 0.5 seconds before the generalized and widespread bilaterally synchronous spike-wave discharges (SWDs) when absence seizure. Focal epileptiform discharges were found in inter-ictal phase from 30 cases of children with seizures. Generalized discharges were observed in in inter-ictal phase from 34 cases:11 cases in awake and sleep period, 20 cases in sleep period, and 3 cases in awake period. Conclusion Focal symptoms, focal epileptiform discharges and focal starting were observed in children with typical absence seizure, so we could not consider a typical absence seizure as a partial onset seizure according to the focal symptoms, focal epileptiform discharges and focal starting in EEG