[P1-83] Characteristics of Migraines in Pediatric Focal Epileptic Syndrome
Characteristics of Migraines in Pediatric Focal Epileptic Syndrome
Background: Epileptic children have higher prevalence of headaches than the general population, which can impair daily activity. The association between migraine and childhood epilepsy has only rarely been studied.
Methods: In this study, 476 out of 865 childhood epilepsy patients presented with focal epileptic syndrome, including 178 frontal lobe epilepsy (FLE), 194 temporal lobe epilepsy (TLE), 35 parietal lobe epilepsy (PLE) and 69 occipital lobe epilepsy (OLE). The characteristics of migraines in these different focal epileptic syndromes were analyzed.
Results: Six out of 178 (3.4%) patients with FLE, 13 out of 194 (6.7%) patients with TLE, 13 out of 35 patients with PLE (37%) and 14 out of 69 patients with OLE (20%) presented with migraines. The incidences of migraine were significantly higher in the OLE and PLE groups than in the FLE and TLE groups (p=0.000; odds ratios = 5.08). In idiopathic PLE and OLE patients, more headaches were classified as interictal, in contrast to probable lesional and lesional PLE and OLE patients in which most headaches were classified as periictal. There were higher incidences of seizure drug use and higher seizure frequencies (p<0.05) in children with probable lesional and lesional PLE and OLE with migraine (n=12) than in those without migraine (n=40).
Conclusion: Children with PLE or OLE have higher incidences of migraine than those with FLE or TLE. Moreover, pediatric patients with probable lesional or lesional PLE and OLE with migraine demonstrate more antiepileptic drug use and higher seizure frequencies than those without migraine.
Keywords: migraine; children; epilepsy; focal
Methods: In this study, 476 out of 865 childhood epilepsy patients presented with focal epileptic syndrome, including 178 frontal lobe epilepsy (FLE), 194 temporal lobe epilepsy (TLE), 35 parietal lobe epilepsy (PLE) and 69 occipital lobe epilepsy (OLE). The characteristics of migraines in these different focal epileptic syndromes were analyzed.
Results: Six out of 178 (3.4%) patients with FLE, 13 out of 194 (6.7%) patients with TLE, 13 out of 35 patients with PLE (37%) and 14 out of 69 patients with OLE (20%) presented with migraines. The incidences of migraine were significantly higher in the OLE and PLE groups than in the FLE and TLE groups (p=0.000; odds ratios = 5.08). In idiopathic PLE and OLE patients, more headaches were classified as interictal, in contrast to probable lesional and lesional PLE and OLE patients in which most headaches were classified as periictal. There were higher incidences of seizure drug use and higher seizure frequencies (p<0.05) in children with probable lesional and lesional PLE and OLE with migraine (n=12) than in those without migraine (n=40).
Conclusion: Children with PLE or OLE have higher incidences of migraine than those with FLE or TLE. Moreover, pediatric patients with probable lesional or lesional PLE and OLE with migraine demonstrate more antiepileptic drug use and higher seizure frequencies than those without migraine.
Keywords: migraine; children; epilepsy; focal