[P2-70] Two Tales of Epilepsy-Related Paroxysmal Fast Activities
Paroxysmal fast activities (PFA), generalized or otherwise, can be identified on scalp EEG in a subset of patients with epilepsy. PFA appears to be unique to epilepsy, and may occur either as an interictal feature or as an ictal pattern. Furthermore, interictal and ictal PFA are often quite similar; therefore, their distinction may be difficult if ictal semiology is subtle. Epilepsy associated with PFA is usually drug resistant, suggesting that PFA could be a potential electrophysiological marker of intractability. In our case series, PFA is mainly associated with either Lennox-Gastaut syndrome or intractable focal epilepsy. By examining our experience and reviewing literature, I will discuss the similarities and differences of PFA associated with these two types of epilepsy, and speculate on the pathophysiological mechanisms underlying these electroencephalographic patterns.