[P3-188] Quality of Life assessed by J-KIDSCREEN-52 in children with epilepsy
[Objectives] The purpose of this study was to investigate the self-assessment of health-related quality of life (HRQOL), of children and adolescents with epilepsy. [Methods] We conducted a clinic-based study, in which 429 children without chronic illness (control group) and 281 children with epilepsy (epilepsy group) (8-18years).To assess HRQOL, the Japanese version of KIDSCREEN-52 self-reported questionnaire (J-KIDSCREEN-52), comprises 52 items, each of which is categorized as ten dimensions were used. The Oslo-Social-Scale-3 was used to assess social support. To obtain the information of children with epilepsy, epilepsy-related questionnaires and clinical data were collected from medical record. We used Student’s t-test to compare between the mean of HRQOL scores between control and epilepsy groups. Multivariate logistic regression analysis adjusted by variables were used to evaluate the association of the lower HRQOL in epilepsy group. [Results] The questionnaire was answered by 324 (75.5%) in control group and 174 (61.9%) in epilepsy group. HRQOL in epilepsy group, as compared with those in control group, showed lower mean scores in a dimension (p=0.01). After adjustment for the variables such as age and gender, limitation of daily activities was significantly related to four dimensions of HRQOL, developmental disorder was related to three, and social support weakness was related to eight. [Conclusions] From the child’s self-assessment, lower HRQOL is significantly related to their limitation of daily activities, social support weakness, and developmental disorder. Further studies are needed to examine possible interventions for children and adolescents with epilepsy.