[P3-19] Clinical features of hydrocephalus in 25 cases with purulent meningitis in children
【Background】The severe purulent meningitis still has a high mortality rate and often results in severe sequelae among survivors, especially in children. Recently, the study about the neurological complications of meningitis has attracted more and more concern. The purpose of our study is discussed the clinical features of purulent meningitis with hydrocephalus in children.
【Methods】We Select 267 children with purulent meningitis from pediatric neurology department of Shengjing Hospital of China Medical University, January 2011 through January 2016. We conducted a retrospective study of the clinical features in the cases with hydrocephalus, which were diagnosed by the radiologists’ reports on cranial imaging. 【Results】The morbidity of purulent meningitis with hydrocephalus is higher, the diagnostic rate of neuroradiology is 9.36%（25/267）. Most patients are from rural, the age of onset concentrated under 6 months old, time from onset to diagnosis of hydrocephalus mainly concentrated 1-4 weeks after purulent meningitis, and classified as communicating hydrocephalus. Gram-negative bacteria is mainly pathogenic bacteria. We have found the relationship between CRP, bacterial culture of blood or laboratory indicators of cerebrospinal fluid (CSF) and hydrocephalus through logistic regression analysis. About 56% patients received a previously treatment with antibiotics.
【 Conclusions 】Hydrocephalus is a common complication of purulent meningitis and still has a high incidence. As a pediatrician, correct recognition and treatment of purulent meningitis with hydrocephalus in children are very important.
【Methods】We Select 267 children with purulent meningitis from pediatric neurology department of Shengjing Hospital of China Medical University, January 2011 through January 2016. We conducted a retrospective study of the clinical features in the cases with hydrocephalus, which were diagnosed by the radiologists’ reports on cranial imaging. 【Results】The morbidity of purulent meningitis with hydrocephalus is higher, the diagnostic rate of neuroradiology is 9.36%（25/267）. Most patients are from rural, the age of onset concentrated under 6 months old, time from onset to diagnosis of hydrocephalus mainly concentrated 1-4 weeks after purulent meningitis, and classified as communicating hydrocephalus. Gram-negative bacteria is mainly pathogenic bacteria. We have found the relationship between CRP, bacterial culture of blood or laboratory indicators of cerebrospinal fluid (CSF) and hydrocephalus through logistic regression analysis. About 56% patients received a previously treatment with antibiotics.
【 Conclusions 】Hydrocephalus is a common complication of purulent meningitis and still has a high incidence. As a pediatrician, correct recognition and treatment of purulent meningitis with hydrocephalus in children are very important.