[P3-92] Efficacy of Eye-tracking Device (Eyelink 1000) Compared to DC-EOG to Evaluate Basal Ganglia Function in Tourette Syndrome
[Background] Saccadic recording is helpful for assessing the function of dopaminergic (DA) system in basal ganglia. In our clinic, visually and memory guided saccades (VGS, MGS) have been evaluated in the patients with Segawa’s disease and Gilles de la Tourette syndrome (TS). Saccade recording patients with TS revealed 1) shortened latency of VGS, 2) delayed latency of MGS, and 3) high frequency of saccade to cue (impaired suppression of unwanted saccades). However, the traces of eye movement recorded by DC-EOG were often contaminated by motion artifacts. Therefore, a more accurate recording system which enables to record vertical eye movements was waited for. In 2016, we changed the recording device from DC-EOG to a video-based eye-tracking system (Eyelink 1000). So we evaluated the differences between DC-EOG and Eyelink1000 in the patients with TS. [Methodology] Three male patients with TS, aged 9.6, 11.1 and 14.3 years were examined, respectively. VGS and MGS were recorded by both DC-EOG and Eyelink 1000 simultaneously. [Results] All patients showed that the latency of VGS was shortened and the latency of MGS was similarly delayed in both devices. Because of less motion artifacts, the tracings of Eyelink 1000 were clearer and more accurate than those of DC-EOG. [Conclusion] The evaluation of saccade by Eyelink 1000 was correlated to DC-EOG and was more distinct. Eyelink 1000 is a suitable system for recording eye movements in children. It can also analyze not only horizontally but vertical direction, and is likely to evaluate the saccade more comprehensively in patients with TS.