[P3-95] The role of electroencephalography prior to therapeutic hypothermia in children with cardiac arrest
[Introduction] Electroencephalography (EEG) is useful for determining the indication of therapeutic hypothermia in cases of neonatal hypoxic/ischemic encephalopathy. In children with cardiac arrest, however, the role of EEG prior to therapeutic hypothermia has not been investigated in detail.
[Methods] EEG prior to therapeutic hypothermia was performed in four children with cardiac arrest due to near-drowning accidents. The relationship between the EEG findings and the efficacy of therapeutic hypothermia was investigated.
[Results] (Case 1) A 2-year-old boy drowned in a river, and cardiac arrest continued for 60 minutes. His EEG was flat, and he died 11 days after the accident. (Case 2) A 6-year-old boy drowned in a river, and cardiac arrest continued for 10 minutes. His EEG was flat, and he died 3 days after the accident. (Case 3) A 1-year-old girl drowned during a bath, and cardiac arrest continued for 52 minutes. The background activity on EEG consisted of a central dominant organized 1-Hz delta rhythm. She was left with serious neurological consequences. (Case 4) A 13-year-old boy drowned in a river, and cardiac arrest continued for 10 minutes. The background activity on EEG consisted of a posterior dominant organized 12-Hz alpha rhythm. His consciousness improved, and he recovered without any aftereffects.
[Conclusion] The present results show that the EEG findings were well-correlated with the efficacy of subsequent therapeutic hypothermia in our patients. EEG may be useful as a predictive examination for both the neurological consequences and the efficacy of therapeutic hypothermia in patients with cardiac arrest.
[Methods] EEG prior to therapeutic hypothermia was performed in four children with cardiac arrest due to near-drowning accidents. The relationship between the EEG findings and the efficacy of therapeutic hypothermia was investigated.
[Results] (Case 1) A 2-year-old boy drowned in a river, and cardiac arrest continued for 60 minutes. His EEG was flat, and he died 11 days after the accident. (Case 2) A 6-year-old boy drowned in a river, and cardiac arrest continued for 10 minutes. His EEG was flat, and he died 3 days after the accident. (Case 3) A 1-year-old girl drowned during a bath, and cardiac arrest continued for 52 minutes. The background activity on EEG consisted of a central dominant organized 1-Hz delta rhythm. She was left with serious neurological consequences. (Case 4) A 13-year-old boy drowned in a river, and cardiac arrest continued for 10 minutes. The background activity on EEG consisted of a posterior dominant organized 12-Hz alpha rhythm. His consciousness improved, and he recovered without any aftereffects.
[Conclusion] The present results show that the EEG findings were well-correlated with the efficacy of subsequent therapeutic hypothermia in our patients. EEG may be useful as a predictive examination for both the neurological consequences and the efficacy of therapeutic hypothermia in patients with cardiac arrest.