[PS2-1B-2 ] Clinical aspects on myasthenia gravis in childhood
This review discusses clinical aspects on myasthenia gravis (MG) with onset of childhood
MG in childhood is influenced by genetic and environmental factors. Juvenile MG is associated with antibodies to the acetylcholine receptor (AChR) in most patients. Thymoma is rare. The frequency of MG with antibodies to the musle specific kinase (MuSK) varies markedly in different countries. Some distinct features have been described In most of the cases with MG is ocular type with low level of AChR. According to our previous study about prognosis of MG, A better condition was attained in those patients with the following factors was noticed better to those who did not have them.1.Some precipitationg factors was noted at the onset, 2 Adequate therapy was given within three months after onset, 3.IgG Fc receptor positive T cell were not increased, 4.Aggravating factors such as infection were encountered less frequently during the course of disease. Management of juvenile MG does not differ, in general, from that of adult MG. But timing of thymectomy is still contraversial.
MG in childhood is influenced by genetic and environmental factors. Juvenile MG is associated with antibodies to the acetylcholine receptor (AChR) in most patients. Thymoma is rare. The frequency of MG with antibodies to the musle specific kinase (MuSK) varies markedly in different countries. Some distinct features have been described In most of the cases with MG is ocular type with low level of AChR. According to our previous study about prognosis of MG, A better condition was attained in those patients with the following factors was noticed better to those who did not have them.1.Some precipitationg factors was noted at the onset, 2 Adequate therapy was given within three months after onset, 3.IgG Fc receptor positive T cell were not increased, 4.Aggravating factors such as infection were encountered less frequently during the course of disease. Management of juvenile MG does not differ, in general, from that of adult MG. But timing of thymectomy is still contraversial.