[STS1] Special Topics Seminar 1: Movement Disorder
New vision in pediatric movement disorders

[STS1-4A-4] Genetics of Movement Disorders

^○Wang-Tso Lee (Department of Pediatric Neurology, National Taiwan University Children’s Hospital, Taiwan)

Movement disorders in children can be divided into developmental, hyperkinetic, hypokinetic, or paroxysmal disorders. There are also many movement disorders, which may be secondary to other neurometabolic disorders. Genetic disorders of the central nervous system may lead to movement disorders as parts of the phenotype, or sometimes as the main manifestations. The currently known genetically determined movement disorders include parkinsonism, dystonia, neurodegeneration with brain iron accumulation, inherited ataxia, hereditary spastic paraparesis, and other paroxysmal movement disorders. Neurologists should know that patients with neurological disorders presenting with movement disorders may have a genetic factors. In this review, we will illustrate some important movement disorders in children, possibly be related to genetic mutation.