Academic Program [Oral A]

16. Natural Products Chemistry, Chemical Biology » Oral A

[B104-3vn] 16. Natural Products Chemistry, Chemical Biology

Fri. Mar 25, 2022 4:10 PM - 6:50 PM B104 (Online Meeting)

Chair: Daisuke Takahashi, Yuta Maki

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4:10 PM - 4:20 PM

[B104-3vn-01] Semisynthesis of IL21 based on chemical insertion of glycan

^○Nana Izawa¹, Yuta Maki^1,2, Ryo Okamoto^1,2, Yasuhiro Kajihara^1,2 (1. Sch. Sci., Osaka Univ., 2. Grad. Sch. Sci., PRC, Osaka Univ.)

[Lang.] Japanese

4:20 PM - 4:30 PM

[B104-3vn-02] Synthesis of a fluoroamino acid toward the functional study of glycoprotein interaction

^○Ryota Sakurai¹, Ryo Okamoto^1,2, Yuta Maki^1,2, Yasuhiro Kajihara^1,2 (1. Sch. Sci., Osaka Univ., 2. PRC, Grad. Sci., Osaka Univ.)

[Lang.] Japanese

4:30 PM - 4:40 PM

[B104-3vn-03] Semisynthesis of Chondroitin Sulfate Library for Evaluation of the Biological Activity

^○Mina Yoshida¹, Atsumi Koba¹, Shotaro Matsui¹, Yuta Maki^1,2, Ryo Okamoto^1,2, Yasuhiro Kajihara^1,2 (1. Dept. Chem., Grad. Sch. Sci., Osaka Univ., 2. PRC, Grad. Sch. Sci., Osaka Univ.)

[Lang.] Japanese

4:40 PM - 4:50 PM

[B104-3vn-04] Development and Application of BF₃･Et₂O-Catalyzed Glycosylation Using Glycosyl Fluorides

^○Takuya Matsumoto¹, Yoshiyuki Manabe¹, Yuka Ikinaga¹, Yuya Tsutsui¹, Yuichiro Kadonaga¹, Akihito Konishi¹, Makoto Yasuda¹, Koichi Fukase¹ (1. The Univ. of Osaka)

[Lang.] Japanese

4:50 PM - 5:00 PM

[B104-3vn-05] Chemical synthesis and function of Campylobacter jejuni lipid As

^○Toshinori Fujie¹, Sho Nakagawa, Yoshihumi Matsuura¹, Atsushi Shimoyama¹, Koichi Fukase¹ (1. Osaka University)

[Lang.] Japanese

5:00 PM - 5:10 PM

[B104-3vn-06] Synthesis of fluorescent labeled dolichol-phosphate mannose for analyzing post-translational mannosylation mechanism

^○Kohtaro Hirao¹, Yoshiyuki Manabe^1,2, Kazuya Kabayama^1,2, Koichi Fukase^1,2 (1. Graduate School of Osaka University, 2. Project Research Center for Fundamental Sciences, Osaka University)

[Lang.] Japanese

5:10 PM - 5:20 PM

[B104-3vn-07] One-pot electrochemical synthesis of cyclic oligosaccharides named "cyclokasaodorin" from D-glucosamine

^○Hirofumi Endo¹, Masaharu Ochi¹, Azadur Md Rahman¹, Tomoaki Hamada², Takahiro Kawano², Toshiki Nokami¹ (1. Tottori University , 2. KOGANEI Corporation)

[Lang.] Japanese

5:20 PM - 5:30 PM

[B104-3vn-08] Synthetic study of oligosaccharides containing N-glycosyl neuraminic acids by using a sialyl donor possessing a N-acyl cyclic carbonate

^○Yutaka Takeuchi¹, Hiroshi Tanaka¹, Kazuki Tohda¹ (1. Tokyo Institute of Technology)

[Lang.] Japanese

5:30 PM - 5:40 PM

[B104-3vn-09] Synthesis and Functional Evaluation of α(1,2) mannoside (Mannan cap) to Bactericidal Evasion of Mycobacterium tuberculosis

^○Kazuya Murakami¹, Mai Watanabe¹, Kei Hanahusa², Hitoshi Nakayama², Kazuhisa Iwabuchi², Hiroshi Tanaka¹ (1. Tokyo Institute of technology, 2. Juntendo university)

[Lang.] Japanese

5:40 PM - 5:50 PM

[B104-3vn-10] Development of the small molecules interacted with polysialic acids and their structure-activity relationships.

^○Keita Ouchi¹, Miki Imai¹, Masaya Hane², Ken Kitajima², Chihiro Sato², Hiroshi Tanaka¹ (1. Tokyo Institute of Technologyte, 2. Nagoya University)

[Lang.] Japanese

5:50 PM - 6:00 PM

[B104-3vn-11] Synthesis of Oligosaccharide derived from Pathogenic Escherichia Coli O1–Protein Conjugates and Identification of a Glycotope of Avian Pathogenic Escherichia Coli O1

^○Katsunori Seki¹, Takumi Makikawa¹, Daisuke Takahashi¹, Kazunobu Toshima¹ (1. Fac. Sci. Tech., Keio Univ.)

[Lang.] Japanese

6:00 PM - 6:10 PM

[B104-3vn-12] Synthesis of Mannosylerythritol Lipid Derivatives and Their Recovery Effects on the Damaged Cultured Human Skin Cells

^○Chihiro Yasui¹, Takanori Kondo¹, Tomotake Morita², Daisuke Takahashi¹, Kazunobu Toshima¹ (1. Fac. Sci. Tech., Keio Univ., 2. AIST)

[Lang.] Japanese

6:10 PM - 6:20 PM

[B104-3vn-13] Importance of the pyrophosphate group of the glycolipid MPIase essential for membrane protein integration in E. coli.

^○Tsukiho Osawa¹, Kohki Fujikawa¹, Youjung Han², Ken-ichi Nishiyama², Keiko Shimamoto¹ (1. Bioorg. Res. Inst, SUNTORY Foundation for Life Sciences, 2. Faculty of Agriculture, Iwate Univ.)

[Lang.] Japanese

6:20 PM - 6:30 PM

[B104-3vn-14] Synthetic study on arabinofuranosylated probes for functional analysis of novel exo-β-D-arabinofuranosidase

^○Akihiro ISHIWATA¹, Kiyotaka FUJITA², Katsunori Tanaka^1,3,4, Yukishige ITO^1,5 (1. RIKEN, 2. Kagoshima Univ., 3. Tokyo, 4. Kazen Fed. Univ., 5. Osaka Univ.)

[Lang.] Japanese

6:30 PM - 6:40 PM

[B104-3vn-15] Synthetic study of hybrid-binding probe towards endo-glycosydase activity mediated by Ces1d

^○Akito Taira¹, Taiki Kuribara¹, Kiichiro Totani¹ (1. The Univ. of Seikei)

[Lang.] Japanese

6:40 PM - 6:50 PM

[B104-3vn-16] Synthesis of Cyclic Peptide Thioester and their use in Native Chemical Ligation

Yusuke Nakamura¹, Yasuhito Akai¹, Yuma Fujisaka¹, ^○Masayuki Izumi¹ (1. Kochi University)

[Lang.] Japanese

Session information

[B104-3vn] 16. Natural Products Chemistry, Chemical Biology

[B104-3vn-01] Semisynthesis of IL21 based on chemical insertion of glycan

[B104-3vn-02] Synthesis of a fluoroamino acid toward the functional study of glycoprotein interaction

[B104-3vn-03] Semisynthesis of Chondroitin Sulfate Library for Evaluation of the Biological Activity

[B104-3vn-04] Development and Application of BF₃･Et₂O-Catalyzed Glycosylation Using Glycosyl Fluorides

[B104-3vn-05] Chemical synthesis and function of Campylobacter jejuni lipid As

[B104-3vn-06] Synthesis of fluorescent labeled dolichol-phosphate mannose for analyzing post-translational mannosylation mechanism

[B104-3vn-07] One-pot electrochemical synthesis of cyclic oligosaccharides named "cyclokasaodorin" from D-glucosamine

[B104-3vn-08] Synthetic study of oligosaccharides containing N-glycosyl neuraminic acids by using a sialyl donor possessing a N-acyl cyclic carbonate

[B104-3vn-09] Synthesis and Functional Evaluation of α(1,2) mannoside (Mannan cap) to Bactericidal Evasion of Mycobacterium tuberculosis

[B104-3vn-10] Development of the small molecules interacted with polysialic acids and their structure-activity relationships.

[B104-3vn-11] Synthesis of Oligosaccharide derived from Pathogenic Escherichia Coli O1–Protein Conjugates and Identification of a Glycotope of Avian Pathogenic Escherichia Coli O1

[B104-3vn-12] Synthesis of Mannosylerythritol Lipid Derivatives and Their Recovery Effects on the Damaged Cultured Human Skin Cells

[B104-3vn-13] Importance of the pyrophosphate group of the glycolipid MPIase essential for membrane protein integration in E. coli.

[B104-3vn-14] Synthetic study on arabinofuranosylated probes for functional analysis of novel exo-β-D-arabinofuranosidase

[B104-3vn-15] Synthetic study of hybrid-binding probe towards endo-glycosydase activity mediated by Ces1d

[B104-3vn-16] Synthesis of Cyclic Peptide Thioester and their use in Native Chemical Ligation

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