Academic Program [Oral A]

16. Natural Products Chemistry, Chemical Biology » Oral A

[D1442-4am] 16. Natural Products Chemistry, Chemical Biology

Sat. Mar 25, 2023 9:00 AM - 11:20 AM D1442 (1442, Bldg. 14 [4F])

Chair: Masahumi Minoshima, Tomohiro Doura

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9:00 AM - 9:10 AM

[D1442-4am-01] Rational design of an orthogonal pair of diterpene glycoside fusicoccin and 14-3-3 protein

^○Kiriyama Hironaru¹, Ohkanda Junko¹ (1. Shinshu Univ.)

[Lang.] Japanese

9:10 AM - 9:20 AM

[D1442-4am-02] Bioactivity and bioactive form of cis-OPDA, plant hormone biosynthetic precursor

^○Tsumugi Kitajima¹, Rina Saito³, Yuho Nishizato², Misuzu Nakayama², Nobuki Kato², Yousuke Takaoka², Hidenori Yoshimatsu², Minoru Ueda^2,3 (1. Faculty of Sciences, Tohoku University, 2. Graduate School of Sciences, Tohoku University, 3. Graduate School of Life Sciences, Tohoku University)

[Lang.] Japanese

9:20 AM - 9:30 AM

[D1442-4am-03] Investigation of diazo compounds reactivity with a biotolerant metal catalyst

^○Koya Okumura¹, Ambara Rachmat Pradipta¹, Katsunori Tanaka^1,2 (1. Tokyo Institute of Technology, School of Materials and Chemical Technology, Department of Chemical Science and Engineering, 2. RIKEN Cluster for Pioneering Research, Biofunctional Synthetic Chemistry Laboratory)

[Lang.] Japanese

9:30 AM - 9:40 AM

[D1442-4am-04] Examination of Lewis acid-catalyzed reaction in vivo

^○Ren KUMAKURA¹, Ambara Rachmat PRADIPTA¹, Katsunori TANAKA^1,2 (1. Tokyo Institute of Technology, School of Materials and Chemical Technology, Department of Chemical Science and Engineering, 2. RIKEN Cluster for Pioneering Research, Biofunctional Synthetic Chemistry Laboratory)

[Lang.] Japanese

9:40 AM - 9:50 AM

[D1442-4am-05] Glycan chemical knock-in based on proximity labeling: application to cancer immune therapy

^○Takuya Matsumoto¹, Yoshiyuki Manabe^1,2, Koichi Fukase^1,2 (1. Osaka University graduate school of science, 2. Osaka University Basic Science Project Research Center)

[Lang.] Japanese

9:50 AM - 10:00 AM

[D1442-4am-06] Construction of N-containing heteroaromatics via photo-induced N-O cleavage

^○Yui Kaneyama^1,2, Okamura Hidenori^1,2, Iida Momoka^1,2, Kawamori Arisa^1,2, Nagatsugi Fumi¹ (1. IMRAM, Tohoku Univ., 2. Grad. Sch. Sci, Tohoku Univ.)

[Lang.] Japanese

Break (10:00 AM - 10:10 AM)

10:10 AM - 10:20 AM

[D1442-4am-07] Development of Glyco-Nanoadjunvats that consisted of gold nanoparticles co-immobilized with synthetic TLR9 ligand and sugar molecule

^○Koki Murata¹, Mayuko Shimoda², Toshiro Moroishi^2,3 (1. Grad. Sch. Sci. and Eng., Kagoshima Univ., 2. Dept. Mol. and Med. Pharmacol., Fac. Life Sci., Kumamoto Univ., 3. CMRHA, Fac. Life Sci., Kumamoto Univ.)

[Lang.] Japanese

10:20 AM - 10:30 AM

[D1442-4am-08] Synthetic study of anticancer molecules using gold-catalyst in brain

^○Moeri HARA¹, Yudai ODE¹, Sayaka URANO², Akari MUKAIMINE², Tsung-Che CHANG², Ambara Rachmat PRADIPTA¹, Katsunori TANAKA^1,2 (1. Tokyo Institute of Technology, School of Materials and Chemical Technology, Department of Chemical Science and Engineering, 2. RIKEN Cluster for Pioneering Research, Biofunctional Synthetic Chemistry Laboratory )

[Lang.] Japanese

10:30 AM - 10:40 AM

[D1442-4am-09] Conversion of biogenic cancer metabolites into an anticancer compound in living cells

^○Masayuki KAWAI¹, Ambara Rachmat PRADIPTA¹, Katsunori TANAKA^1,2 (1. Tokyo Institute of Technology, School of Materials and Chemical Technology, Department of Chemical Science and Engineering, 2. RIKEN Cluster for Pioneering Research, Biofunctional Synthetic Chemistry Laboratory)

[Lang.] Japanese

10:40 AM - 10:50 AM

[D1442-4am-10] Synthesis and evaluation of catechol derivatives as an amyloid-beta aggregation inhibitor

^○fusheng xu¹, miyu okada¹, hiroyuki konno¹ (1. The Univ. of Yamagata)

[Lang.] English

10:50 AM - 11:00 AM

[D1442-4am-11] Development of prodrugs using the Diels-Alder reaction in vivo

^○Kaito Hattori¹, Hiroyuki Michiba¹, Ambara Rachmat PRADIPTA¹, Katsunori Tanaka^1,2 (1. Tokyo Institute of Technology, School of Materials and Chemical Technology, Department of Chemical Science and Engineering, 2. RIKEN Cluster for Pioneering Research, Biofunctional Synthetic Chemistry Laboratory)

[Lang.] Japanese

11:00 AM - 11:10 AM

[D1442-4am-12] Development of bi-substrate mimicking FUT8 inhibitor for regulating core fucose function

^○Koki Hizume¹, Yoshiyuki Manabe¹, Mayu Yanagihara¹, Yohei Takakura¹, Satomi Kasahara¹, Koichi Fukase¹ (1. Graduate School of Science, Osaka University)

[Lang.] Japanese

11:10 AM - 11:20 AM

[D1442-4am-13] Development of protein labeling probes containing bioisostere to suppress nonspecific accumulation in organelles

^○Takuya Kamikawa¹, Kazuya Kikuchi^2,3, Yuichiro Hori¹ (1. Graduate School of Science, Kyushu University, 2. Graduate School of Engineering, Osaka University, 3. Immunology Frontier Research Center, Osaka University)

[Lang.] Japanese

Session information

[D1442-4am] 16. Natural Products Chemistry, Chemical Biology

[D1442-4am-01] Rational design of an orthogonal pair of diterpene glycoside fusicoccin and 14-3-3 protein

[D1442-4am-02] Bioactivity and bioactive form of cis-OPDA, plant hormone biosynthetic precursor

[D1442-4am-03] Investigation of diazo compounds reactivity with a biotolerant metal catalyst

[D1442-4am-04] Examination of Lewis acid-catalyzed reaction in vivo

[D1442-4am-05] Glycan chemical knock-in based on proximity labeling: application to cancer immune therapy

[D1442-4am-06] Construction of N-containing heteroaromatics via photo-induced N-O cleavage

[D1442-4am-07] Development of Glyco-Nanoadjunvats that consisted of gold nanoparticles co-immobilized with synthetic TLR9 ligand and sugar molecule

[D1442-4am-08] Synthetic study of anticancer molecules using gold-catalyst in brain

[D1442-4am-09] Conversion of biogenic cancer metabolites into an anticancer compound in living cells

[D1442-4am-10] Synthesis and evaluation of catechol derivatives as an amyloid-beta aggregation inhibitor

[D1442-4am-11] Development of prodrugs using the Diels-Alder reaction in vivo

[D1442-4am-12] Development of bi-substrate mimicking FUT8 inhibitor for regulating core fucose function

[D1442-4am-13] Development of protein labeling probes containing bioisostere to suppress nonspecific accumulation in organelles

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