Catalytic Hydroxylation of Non-native Substrates by Cytochrome P450BM3 Mutants with Expanded Structural Availability of Decoy Molecules by Directed Evolution

Yuya Yokoyama

Presentation information

Academic Program [Oral B]

17. Biofunctional Chemistry, Biotechnology » Oral B

[E1661-4am] 17. Biofunctional Chemistry, Biotechnology

Sat. Mar 25, 2023 9:00 AM - 11:10 AM E1661 (1611, Bldg. 16 [1F])

Chair: Nobuhiko Hosono, Takashi Matsuo

10:10 AM - 10:30 AM

[E1661-4am-04] Catalytic Hydroxylation of Non-native Substrates by Cytochrome P450BM3 Mutants with Expanded Structural Availability of Decoy Molecules by Directed Evolution

^○Yuya Yokoyama¹, Shinya Ariyasu¹, Masayuki Karasawa¹, Kai Yonemura¹, Yuichiro Aiba¹, Hiroshi Sugimoto², Osami Shoji¹ (1. School of Science, Nagoya University, 2. RIKEN SPring-8)

[Lang.] English

Keywords:Cytochrome P450, Decoy Molecules, Directed Evolution, N-Acyl Homoserine Lactones, Hydroxylation Reaction