[15p-2A-1~22] 12.6 Nanobiotechnology

△ [15p-2A-12] Fluorescence Analysis of Optical Trapping of Single Nanoparticles on a Plasmonic Chip

〇(M2)Kohei Miyauchi^1,2, Keiko Tawa^2,1, Suguru N.Kudoh², Takahisa Taguchi³, Chie Hosokawa^1,2 (1.AIST, 2.Kwansei Gakuin Univ., 3.NICT)

Keywords:optical tweezers,plasmonic chip,neural cell adhesion molecule

We propose and demonstrate surface plasmon-enhanced optical tweezers toward local manipulation of cell surface molecules on neuronal cells. From fluorescence analysis, the particle motion of quantum-dot nanoparticle suspended in water on plasmonic chip was confined more effectively than that on glass substrate, which is caused by surface plasmon-enhanced optical trapping force.