[20a-A204-1~10] 12.3 Functional Materials and Novel Devices

△ [20a-A204-9] Magneto-responsive particles for NIR excitable SERS substrates

〇Yutaro Hirai¹, Yasutaka Matsuo², Hiroshi Yabu³ (1.Grad. Sch. of Eng. Tohoku Univ., 2.RIES, Hokkaido Univ., 3.WPI-AIMR)

Keywords:SERS, core-shell particles, self-organization

Surface Enhanced Raman Scattering (SERS), which offers high sensitivity to detect single molecule, is often used in biological analysis and medical diagnosis. In order to realizing arbitral observation of local information in cells or tissues by Raman scattering, NIR excitable SERS substrates having high tissue transparency and positional control of enhanced sites are required. We prepared polymer core-shell particles, which were composed of polystyrene and amino-terminated polybutadiene, having magnetic nanoparticles in the core and gold nanoparticles (diameter = 20~80 nm) densely packed in the shell by using Self-ORganized Precipitation (SORP) method. Absorbance of composite particle was red-shifted as the diameter of introduced gold nanoparticles increased. These particles were magneto-responsive and showed SERS signal from adsorbed molecules by using NIR excitation (λ=785 nm). In particular, especially high signal intensity was shown when the size of introduced Au NPs is 50 nm, because stronger electro-magnetic field enhancement was occurred since absorption peak of composite particles and excitation wavelength was well matched.