Quantitative prediction of hepatic uptake clearance mediated by organic anion transporting polypeptide (OATP) 1B1 and OATP1B3 using relative activity factor-based scaling approach

Saki Izumi

Presentation information

Oral Presentation

[O1] 1．Transporter 1

Thu. Oct 13, 2016 9:00 AM - 10:12 AM Room 5 (The first meeting room)

Seiji Miyauchi (Toho University, Faculty of Pharmaceutical Sciences, Department of Pharmacokinetics), Takeshi Hirota (Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University), Takuo Ogihara (Laboratory of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Takasaki University of Health and Welfare), Takuya Fujita (Department of Molecular Pharmacokinetics, College of Pharmaceutical Sciences, Ritsumeikan University), )

[O1-5] Quantitative prediction of hepatic uptake clearance mediated by organic anion transporting polypeptide (OATP) 1B1 and OATP1B3 using relative activity factor-based scaling approach

Saki Izumi ¹, Yoshitane Nozaki ¹, Takafumi Komori ¹, Kazuya Maeda ², Hiroyuki Kusuhara ², Yuichi Sugiyama ³ (1.Eisai Co., Ltd., 2.Graduate School of Pharmaceutical Sciences, The University of Tokyo, 3.RIKEN Innovation Center, RIKEN)

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