Oral

[O2-4] Hepatitis 8

Wed. Oct 30, 2019 4:45 PM - 5:45 PM Room 4 (Heian)

Chair：
Isogawa Masanori (Department of Virology,Nagoya City University Graduate School of Medical Sciences,)
Kei Miyakawa (Department of Microbiology and Molecular Biodefense Research, School of Medicine, Yokohama City University)

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4:45 PM - 5:00 PM

[O2-4-11] Epitope analysis of monoclonal antibodies against hepatitis B virus receptor binding region

*Keigo Yato^1,2, Taishi Onodera³, Mami Matsuda¹, Akira Fujimoto⁴, Koichi Watashi¹, Hideki Aizaki¹, Takanobu Kato¹, Kohji Moriishi⁵, Koji Tamura², Yoshimasa Takahashi³, Takaji Wakita¹, Masamichi Muramatsu¹, Ryosuke Suzuki^1,2 (1. Department of Virology II, National Institute of Infectious Diseases, 2. Department of Biological Science and Technology, Tokyo University of Science, 3. Department of Immunology, National Institute of Infectious Diseases, 4. Department of Infection Control and Immunology, The Kitasato Institute for Life Sciences, 5. Department of Microbiology, Division of Medicine, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi)

5:00 PM - 5:15 PM

[O2-4-12] Analysis of physicochemical property, replication, and pathophysiology of an HBsAg escaped hepatitis B virus (HBV)

*Md. Golzar Hossain¹, Keiji Ueda¹ (1. Division of Virology, Department of Microbiology and Immunology, Graduate School of Medicine, Osaka University, Japan)

5:15 PM - 5:30 PM

[O2-4-13] ISGylation of HBx protein confers the pro-viral effects on HBV replication and resistance to interferon (IFN)-response

*Rheza Gandi Bawono¹, Takayuki Abe¹, Lin Deng¹, Chieko Matsui¹, Kunitada Shimotohno², Ikuo Shoji¹ (1. Division of Infectious Disease Control, Center for Infectious Diseases, Kobe University Graduate School of Medicine, Kobe, Japan, 2. Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, Ichikawa, Japan)

5:30 PM - 5:45 PM

[O2-4-14] Unfolded protein response activation prevents IFN-mediated liver injury associated with the large hepatitis B surface antigen accumulation.

*Ian Baudi¹, Masanori Isogawa¹, Keigo Kawashima¹, Yasuhito Tanaka¹ (1. Department of Virology, Nagoya City Universty Graduate School of Medical Sciences. )

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