[26E2-pm] Drug design

Sun. Mar 26, 2023 1:50 PM - 2:50 PM [Room E2]Institute for the Advancement of Higher Education: E308 (Bldg. E: 3F)

Chair: Shino Manabe, Tsubasa Inokuma

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1:50 PM - 2:02 PM

[26E2-pm01S] Functional-protein-Drug Conjugates with Photoresponsive Self-inactivation Mechanisms

○Kazuki Takahashi¹, Toshifumi Tatsumi¹, Masazumi Ishii², Toshiya Tanaka², Tatsuhiko Kodama², Akira Sugiyama^2,3, Kenzo Yamatsugu¹, Motomu Kanai¹ (1. Grad. Sch. Pharm. Sci., Univ. of Tokyo, 2. RCAST, Univ. of Tokyo, 3. Isotope Science Center, Univ. of Tokyo)

2:02 PM - 2:14 PM

[26E2-pm02S] Design, Synthesis, and Anticancer Activity of Triptycene-Peptide Hybrids with Peptides that Localize to Mitochondria

○Mayuka Nii¹, Kohei Yamaguchi¹, Kenta Yokoi¹, Shin Aoki^1,2 (1. Faculty of Pharm. Sci., Tokyo University of Science, 2. Research Institute for Science and Technology, Tokyo University of Science)

2:14 PM - 2:26 PM

[26E2-pm03S] Structural optimization of the drug-linker with S-trityl-_L-cysteine derivatives for antibody-drug conjugates

○Taiki Ichida¹, Ryota Fukai¹, Kesuke Murase¹, Nao Miyoshi¹, Hisashi Murakami¹, Naohisa Ogo¹, Akira Asai¹ (1. Grad. Div. Pharm., Univ. of Shizuoka)

2:26 PM - 2:38 PM

[26E2-pm04] Peptide-Drug Conjugate: Targeted Intracellular Drug Delivery by VEGF-Targeting Helix–Loop–Helix Peptide via Receptor-Mediated Endocytosis

○Masataka Michigami¹, Masayuki Kamo², Takatsugu Hirokawa³, Koji Inaka², Ikuhiko Nakase¹, Ikuo Fujii¹ (1. Grad. Sch. Sci., Osaka Metropolitan Univ., 2. MARUWA Foods and Biosciences Inc., 3. Fac. med., Tsukuba Univ.)

2:38 PM - 2:50 PM

[26E2-pm05S] Generation of the molecular targeting HLH peptides for inhibitors against nuclear receptors.

○Ken Kumasaki¹, Shunsuke Inaura², Yuna Tanaka¹, Maaki Wakita², Sayoko Harasima³, Masataka Mitigami¹, Daisuke Fujiwara¹, Ikuhiko Nakase¹, Ikuo Fujii¹ (1. Grad. Sch. Sci. Osaka Met. Univ., 2. Grad. Sch. Sci. Osaka Pre. Univ., 3. Grad. Sch. Agr. Osaka Met. Univ.)

Session information

[26E2-pm] Drug design

[26E2-pm01S] Functional-protein-Drug Conjugates with Photoresponsive Self-inactivation Mechanisms

[26E2-pm02S] Design, Synthesis, and Anticancer Activity of Triptycene-Peptide Hybrids with Peptides that Localize to Mitochondria

[26E2-pm03S] Structural optimization of the drug-linker with S-trityl-_L-cysteine derivatives for antibody-drug conjugates

[26E2-pm04] Peptide-Drug Conjugate: Targeted Intracellular Drug Delivery by VEGF-Targeting Helix–Loop–Helix Peptide via Receptor-Mediated Endocytosis

[26E2-pm05S] Generation of the molecular targeting HLH peptides for inhibitors against nuclear receptors.

Authentication

Session information

[26E2-pm] Drug design

[26E2-pm01S] Functional-protein-Drug Conjugates with Photoresponsive Self-inactivation Mechanisms

[26E2-pm02S] Design, Synthesis, and Anticancer Activity of Triptycene-Peptide Hybrids with Peptides that Localize to Mitochondria

[26E2-pm03S] Structural optimization of the drug-linker with S-trityl-L-cysteine derivatives for antibody-drug conjugates

[26E2-pm04] Peptide-Drug Conjugate: Targeted Intracellular Drug Delivery by VEGF-Targeting Helix–Loop–Helix Peptide via Receptor-Mediated Endocytosis

[26E2-pm05S] Generation of the molecular targeting HLH peptides for inhibitors against nuclear receptors.

Authentication

[26E2-pm03S] Structural optimization of the drug-linker with S-trityl-_L-cysteine derivatives for antibody-drug conjugates