[26E4-am] Genes/Biosynthesis/Others

Sun. Mar 26, 2023 11:00 AM - 12:00 PM [Room E4] Institute for the Advancement of Higher Education: E311 (Bldg. E: 3F)

Chair: Teigo Asai, Richiro Ushimaru

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11:00 AM - 11:12 AM

[26E4-am11S] Non-enzymatic Formation of Chaxines and Natural Steroidal Derivatives via Ergosterol Air Oxidation

○Ryota Namba¹, Shinji Kishimoto¹, Pengchen Ma², Toshio Nishikawa³, Hideaki Oikawa⁴, Hirokazu Kawagishi^1,5, Kendll Newcomb Houk², Kenji Watanabe¹ (1. Department of Pharmaceutical Sciences, University of Shizuoka, 2. UCLA, Chem and Biochem, 3. Graduate School of Bioagricultural Sciences, Nagoya University, 4. Department of Chemistry Graduate School of Science, Hokkaido University, 5. RIGST, Shizuoka University)

11:12 AM - 11:24 AM

[26E4-am12S] Biosynthetic study on natural products from actinomycetes through an OSMAC methodology

○Yuki Kobayashi¹, Ryota Endo¹, Michio Sato¹, Julius Lopez², Toshihiko Nogawa², Hiroyuki Osada^1,2, Kenji Watanabe¹ (1. Department of Pharmaceutical Sciences, University of Shizuoka, 2. RIKEN)

11:24 AM - 11:36 AM

[26E4-am13S] Search for the extracellular enzyme responsible for the conversion of lagopodin B to hitoyol A, a compound from the basidiomycete Coprinopsis sp.

○Fumiya Suzuki¹, Shihori Asai¹, Ryota Endo¹, Yuta Tsunematsu¹, Kenji Watanabe¹ (1. University of Shizuoka)

11:36 AM - 11:48 AM

[26E4-am14S] Elucidation of the mechanism for azlactone-forming enzyme

○Yoshimitsu Aoki¹, Ayumi Minami¹, Shinji Kishimoto¹, Kenji Watanabe¹ (1. Department of Pharmaceutical Sciences, University of Shizuoka)

11:48 AM - 12:00 PM

[26E4-am15S] Self-resistance enzyme identified as a target of immunosuppressant (-)–FR901483

○Sakurako Saknao¹, Miku Nakahara¹, Yui Tamura¹, Michio Sato¹, Kodai Hara¹, Hiroshi Hashimoto¹, TANG Yi², Kenji Watanabe¹ (1. University of Shizuoka, 2. University of California, Los Angeles)

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