Oral Presentation

[26F3-pm] Translation of genes/Post-translational modification/Others

Sun. Mar 26, 2023 5:00 PM - 6:24 PM [Room F3] Frontier Research in Applied Sciences Building: Seminar Room 2 (2F)

Chair: Akihiro Ito, Hitomi Tsuiji

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5:00 PM - 5:12 PM

[26F3-pm13] Inhibition of the human tryptophan hydroxylase 2 (TPH2) translation by a 75-nt element embedded in the coding exon 3

○Tomoko Hiroi¹, Hanae Kaneko¹, Masanori Ootaki², Yukino Nawa¹, Masaaki Tsubonoya¹, Naoki Matsumoto², Tomoo Sato¹, Hiroaki Matsui¹ (1. Inst. Radioisotope Res., St. Marianna Univ. Grad. Sch. Med., 2. Dept. Pharm., St. Marianna Univ. Sch. Med.)

5:12 PM - 5:24 PM

[26F3-pm14S] Biological evaluation of negamycin derivatives focusing on nonsense mutation of tumor suppressor gene TP53

○Ayaka Ema¹, Noriko Omura¹, Akihiro Taguchi¹, Keisuke Hamada¹, Yukari Inoue¹, Sho Konno¹, Kentaro Takayama², Atsuhiko Taniguchi¹, Yoshio Hayashi¹ (1. Sch. Pharm., Tokyo Univ. of Pham. and Life Sci., 2. Kyoto Pharm. Univ.)

5:24 PM - 5:36 PM

[26F3-pm15S] Readthrough effect of negamycin derivatives against nonsense mutations derived from muscular dystrophy.

○Noriko Omura¹, Akihiro Taguchi¹, Keisuke Hamada¹, Sho Konno¹, Atsuhiko Taniguchi¹, Yoshio Hayashi¹ (1. Sch. Pharm., Tokyo Univ. of Pharm. and Life Sci. )

5:36 PM - 5:48 PM

[26F3-pm16S] Identification of genes whose expression levels are enhanced by polyamines at the level of translation in mammalian cells

○Masato Suzuki¹, Takehiro Suzuki², Hitomi Manaka¹, Ken Matsumoto², Masahiro Komeno³, Akira Sato³, Naoshi Dohmae², Kazuei Igarashi⁴, Kyohei Higashi³ (1. Grad. Sch. Fac. Pharm. Sci., Tokyo Univ. Sci., 2. RIKEN CSRS, 3. Fac. Pharm. Sci., Tokyo Univ. Sci. , 4. Amine Pharm. Res. Inst.)

5:48 PM - 6:00 PM

[26F3-pm17] Curcumin partly prevents ISG15 activation via ubiquitin-activating enzyme E1-like protein and decreases ISGylation

○Fumihiko Okumura¹, Nodoka Oki ², Shino Yamada ¹, Tamaki Tanaka ¹, Hiromi Fukui ¹, Shigetsugu Hatakeyama² (1. Dep. of Food and Health Sci., Int. Col. of Arts and Sci., Fukuoka Women's Univ. , 2. Dep. of Biochem., Grad. Sch. of Med., Hokkaido Univ.,)

6:00 PM - 6:12 PM

[26F3-pm18S] Analysis of NOTCH3 CADASIL mutant protein aggregation and gylcosylation

○Shodai Suzuki¹, Yohei Tsukamoto², Taiki Mashiko¹, Hideyuki Takeuchi³, Tetsuya Okajima^2,4, Motoyuki Itoh¹ (1. Grad. Sch. Pharm. Sci., Chiba Univ., 2. Grad. Sch. Med., Nagoya Univ., 3. Grad. Sch. Pharm. Sci., Univ. of Shizuoka, 4. iGCORE, Grad. Sch. Med., Nagoya Univ. )

6:12 PM - 6:24 PM

[26F3-pm19S] Regulation and function of glioblastoma epitranscriptomics by RNA demethylase ALKBH3

○Manami Yamada¹, Yuki Shimada¹, Yuki Kinoshita¹, Kaori Kitae², Hiroaki Hase², Yuko Ueda², Kentaro Jingushi², Kazutake Tsujikawa² (1. Sch. Pharm. Sci., Osaka Univ., 2. Grad. Sch. Pharm. Sci., Osaka Univ.)

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